What is phospholipidosis?

phospholipidosis is a condition characterized by the accumulation of phospholipids in the body tissues. These compounds are usually part of the cell wall and skeleton and are continuously present at low levels, but in people with this condition these levels increase very high. This contributes to the development of structures known as myeloid bodies. These structures can be observed in microscopic tissue tests and can be used to diagnose patients with phospholipidosis.

This condition is a form of fault of lysosomal storage. Lysosomes are structures found inside cells that are responsible for metabolizing waste materials, so they can be secreted. In people with lysosomal storage disorders, lysosomes are unable to perform their work and compounds that normally disintegrate and secrete, are captured in cells. Many of these metabolic disorders are hereditary, but some may be caused by drugs as shown in phospholipidosis.S condition and despite numerous scientific studies there is no mechanism that the FO occursSfolipidosis is not fully understood. In some patients, the condition is solved by itself, especially once the drug is interrupted. In others, it may need specific treatment, such as changing drugs or removing the patient from drugs to recover the body.

This unfavorable reaction of the drug is the cause of concern because the presence of phospholipidosis may be an indicator that other drug metabolites are also built in body tissue instead of being secreted. In patients with the diagnosis of this disease, the physician may recommend testing for liver and kidney function to see if these organs have problems with drug metabolization and other compounds that enter the body. If these organs have become endangered, a treatment plan should be developed to solve it.

In cases where phospholipidosis is a risk, doctors provide patients with information about complications of drugs and warning symptoms of drug interactions. Can be recommended to test for conThe phospholipid troll in the tissues of the body and doctors are particularly vigilant about the decline in respiratory function and symptoms of liver and kidney disease. It is soon important to identify harmful interactions and reactions of the drug before they cause permanent damage or result in complications that will require extensive treatment.

drugs associated with phospholipidosis include medicines of angina, antidepressants, antimalars and drugs designed to reduce blood cholesterol. The phospholipidosis caused by the drug (Dipl) is a problem for patients with these drugs as well as for other potential side effects and complications.