What Is Sacroiliac Arthritis?

Anti-Sa antibody is an autoantibody that appears in the serum of patients with rheumatoid arthritis and is reported in 1994 by Despres. The target antigen (Sa antigen) was first found in the human spleen, and later found in the human placenta and rheumatoid synovial membrane, which may be a normal tissue component of the human body. Using immunoblot analysis, the molecular weight of Sa antigen in human spleen was 50 kD, while that of human placental Sa antigen was 50 and 55 kD.

Anti-Sa antibody is an autoantibody that appears in the serum of patients with rheumatoid arthritis and is reported in 1994 by Despres. The target antigen (Sa antigen) was first found in the human spleen, and later found in the human placenta and rheumatoid synovial membrane, which may be a normal tissue component of the human body. Using immunoblot analysis, the molecular weight of Sa antigen in human spleen was 50 kD, while that of human placental Sa antigen was 50 and 55 kD.

Name

Anti-Sa antibody

category

Immunology

Anti-Sa antibody normal value

Normal people have negative anti-Sa antibodies.

Clinical significance of anti-Sa antibodies

Abnormal results: rheumatoid arthritis, Sjogren's syndrome, positive.

People to be examined: joint involvement, morning stiffness, accelerated erythrocyte sedimentation, patients with anti-nuclear antibody positive are more severe than those with anti-Sa antibody, or patients with autoimmune disease.

Anti-Sa antibodies considerations

Before the test: Relax and don't be overly nervous.

During the examination: actively cooperate with the doctor.

Not suitable for the crowd: no

Anti-Sa antibody test process

Spleen cells or placental cells were collected and analyzed by immunoblotting. Actively cooperate with the doctor.

Anti-Sa Antibody Related Diseases

Antibodies, rheumatoid arthritis

^[1]