What Is Tubular Adenocarcinoma?

Clinical features are more common in the elderly over the age of 60, without gender differences. The tumor grew slowly without pain and other conscious symptoms. Small size, mostly less than 2cm in diameter. Percussion is clear and active.

Tubular adenoma

Tubular adenoma onset age

Clinical features are more common in the elderly over the age of 60, without gender differences. The tumor grew slowly without pain and other conscious symptoms. Small size, mostly less than 2cm in diameter. Percussion is clear and active.

Tubular adenoma pathological changes

Visual observation of tubular adenoma

It has a complete envelope and a smooth surface. The profile is brown-yellow, with cysts of various sizes, containing mucus.

Microscopic observation of tubular adenoma

Parenchyma: The tumor is composed of columnar or cubic epithelium, arranged in double layers, and kissing each other into an irregular small tubular or narrow trabecular shape. The nucleus is large, oval, uniform in size, and the cytoplasm is eosinophilic. There are no myoepithelial cells around the lumen or trabecula. The lumen contains PAS-positive secretions. Interstitial: Loose, with numerous capillaries and small veins. There is a basement membrane separation between parenchyma and interstitial.

Differential diagnosis of tubular adenoma

Biological characteristics of adenoid cystic carcinoma basal cell adenoma : tumor growth is slow, small in size, and the envelope is intact. Rarely recurrence after surgical resection. Histogenesis: The inner cells are columnar and the outer layers are basal-like cells, which are similar in structure to the excretory tube. It is speculated that the tissue source may be the excretory tube epithelium.

Tubular adenoma, also known as "adenomatous polyp," is the most common type of colorectal adenoma. Tubular adenoma villi account for less than 20%. Adenomas are spherical, ellipsoidal, or irregular in shape, with a smooth or lobed surface, pinkish-colored, solid, and often with pedicles of varying thickness attached to the intestinal mucosa. However, when the tumor is only a few millimeters in size, it can also be broad-based without visible pedicles. The larger the tubular adenoma, the greater the chance of malignancy. When the adenoma is larger than 2 cm, the canceration rate is significantly increased. If the tumor cells have obvious pleomorphism and interstitial and infiltration, they are said to have severe atypical hyperplasia or canceration.

Pathological changes of tubular adenomas: macroscopic observation: complete envelope, smooth surface. The profile is brown-yellow, with cysts of various sizes, containing mucus.

Microscopic observation of tubular adenoma: parenchyma: The tumor is composed of columnar or cubic epithelium, arranged in double layers, and kissing each other into an irregular small tubular or narrow trabecular shape. The nucleus is large, oval, uniform in size, and the cytoplasm is eosinophilic. There are no myoepithelial cells around the lumen or trabecula. The lumen contains PAS-positive secretions. Interstitial: Loose, with numerous capillaries and small veins. There is a basement membrane separation between parenchyma and interstitial.

Tubular adenoma tubular adenoma treatment

In general, endoscopic removal is the preferred method in clinical practice, and snare electrocautery is also feasible. This method has relatively little damage, light response, and good results.