What are the different methotrexate interactions?
Methhotrexate is a drug that is used to treat various conditions caused by abnormally rapid cellular growth, such as psoriasis in which skin cells normally and accumulate into strong spots and cancer in which abnormal cells are formed and affected by normal cells. The drug is considered effective in the treatment of these types of conditions by slowing the production of body cells. Due to numerous interactions of methotrexate with other drugs that tend to occur, the drug is usually prescribed only if it has been found that other drugs are not effective. NSAIDs and salicylates are generally over -the -counter medicines that are mainly used to treat pain and inflammation. When any of these drugs are used in conjunction with methotrexate, it can increase the effect of methotrexate. The main potentially serious complication that may occur in these increased effects is a kidney disorder, which can lead to kidney failure and eventually death if it is not treated.
Another widely used medicine that can cause methotrexate interactions are certain forms of antibiotics, especially those based on penicillin. Antibiotics are usually prescribed to deprive the body of bacterial infections. If antibiotics are used with methotrexate, it may also disrupt the kidney function; Therefore, if the infection is present in the patient, other treatment options, such as the use of another antibiotic or find replacement for methotrexate, will generally be recommended.
diabetes people tend to be at higher risk of developing methotrexate interactions, so medicines are often not recommended unless other effective alternatives are available. Many copper diabetes, such as glimepiride and chlorpropamide, help treat the condition by making the pancreas more insulin, a hormone that helps the body to use glucose as a source of energy to help parts such as liver. Combination of drugs on diabetes with methotrexate mayTo increase one of the levels of drugs and may result in liver damage.
drugs used to treat acne can potentially cause complications when used with methotrexate. Retinol, a form of vitamin A, is a drug that can be recommended in the treatment of mild to medium acne and can increase the efficacy of methotrexate. Isotretinoin, a prescription drug used to treat severe acne, can also interact with methotrexate and cause either drugs to be potentially dangerously high. Skin and methotrexate drugs can increase sunlight more sensitive, so their joining can lead to the sun burns and make the existing skin conditions deteriorate.