What are the medical use of polyclonal antibodies?
Polyclonal antibodies have a wide range of medical uses and are common components of antivenomes, antitoxin and transplant anti -drug drugs. Antibodies are also often used in diagnostic laboratory testing and research. Polyclonal antibodies are often used for their ability to bind or neutralize specific protein.
The antibodies can be produced using polyclonal antibodies. The animal is administered by injections of a small amount of a particular poison, then the animal produces antibodies that attack and neutralize the poison. This course of treatment may be prolonged over months, but after a sufficient number of antibodies in the bloodstream of the animal, blood extracts. Blood rich in antibody is subject to separation, cleaning and further processing to isolation of polyclonal antibodies, which can then be used to treat bite from specific species.
Antitoxin or antiserum can be produced in a similar way. Laborakonservatives injecting animals with a small amount of specifican organism that creates a polyclonal antibody response that neutralizes toxin. Extracted blood is then used as antitoxin for various diseases such as botulism and tetanus. The blood of individuals who download and survive microbe, generated by microbe, may also be used. For example, an ebola treatment is often used by the anti -surviving patients.
Induction or anti -agent agents were also developed from monoclonal and polyclonal antibodies derived from animal subjects. These products are usually administered immediately after transplant surgery. Antibodies in a serum goal and attack T-cells produced in the blood of patients with transplantation. When the agent encounters T-cell, serum antibodies destroy or consume a cell, they inhibit the rejection of the organ and tissue. Studies show that patients receiving induction substances containing polyclonal antibodies are experiencing less sideEffects compared to those who receive products made with monoclonal antibodies.
laboratories often use polyclonal antibodies to detect disease in blood or tissue diseases. Antibodies bind to surface antigens of viruses or cancer cells, and this binding effect is usually visible under microscopic. Such tests are used for the definitive diagnosis of certain types of encephalitis, HIV and Lyme's disease.
The same technique can be used to detect cancer. For example, a test of a specific prostate antigen (PSA) combines blood patients with polyclonal antibodies to identify cancer cells. Scientists also use antibodies to evaluate how cells communicate and interact. Using this method, scientists can be able to determine the difference between cellular activity under normal conditions and if they are subjected to disease processes.