What Are the Medical Uses of Silibinin?
Silibinin capsules are used for the recovery of abnormal liver function in acute and chronic hepatitis and fatty liver.
- Drug Name
- Silybin capsules
- Drug type
- Prescription drugs, medicines for medical workers' injuries
- Use classification
- Other liver disease adjuvant medications
- Silibinin capsules are used for the recovery of abnormal liver function in acute and chronic hepatitis and fatty liver.
Silybin capsule ingredients
- Silybin. Chemical name: 2- [2,3-trans-2,3-dihydro-3- (4-hydroxy-3-methoxyphenyl) -2-hydroxymethyl-1,4-benzodioxy Hexacyclic-6-yl] -2,3-dihydro-3, 5,7-trihydroxy-4H-1-benzopyran-4-one-hydrate.
2- [2,3-trans-2,3-dihydro-3- (4-hydroxy-3-methoxyphenyl) -2- (hydroxymethyl) -1,4-Benzopyran-4-one monchydrate
Chemical Structure:
Molecular formula: C 25 H 22 O 10 · H 2 O
Molecular weight: 500.47
Silybin capsule properties
- Hard capsules, whose contents are off-white or light yellow powder.
Silybin capsule indications
- It is used for the recovery of abnormal liver function in acute and chronic hepatitis and fatty liver.
Silybin capsule specifications
- Each tablet contains 35mg of silybin.
Silybin capsules dosage
- Orally, 2 to 4 capsules three times daily for adults; or as directed by a doctor.
Adverse Reactions of Silybin Capsules
- Mainly manifested as mild gastrointestinal symptoms (nausea, hiccups) and chest tightness.
Silybin capsule contraindications
- still uncertain.
Silybin capsules notes
- Use with caution to those allergic to this product.
Silybin capsules for pregnant and lactating women
- The safety of medication for pregnant and lactating women has not been determined, please follow your doctor's advice.
Silybin capsules for children
- No adverse reactions have been reported, please follow your doctor's advice.
Silybin capsules for elderly
- No adverse reactions have been reported, please follow your doctor's advice.
Silybin capsule drug interactions
- still uncertain
Silybin capsule overdose
- No adverse reactions have been reported, please follow your doctor's advice.
Silybin capsule pharmacology and toxicology
- Pharmacological effects: Silybin can stabilize liver cell membranes, protect the enzyme system of liver cells, remove reactive oxygen free radicals in liver cells, thereby improving the detoxification ability of the liver and avoiding long-term exposure of liver cells to poisons. He was harmed by taking hepatotoxic drugs, smoking or drinking.
Silybin Capsule Pharmacokinetics
- According to reports, after taking silibinin lecithin complex 360mg (as silibinin) in healthy people, the peak free blood concentration was 298 ± 96ng / ml, and the peak time was 1.6 ± 0.3h. Residual time is 3.6 ± 0.4h, AUC ( 0-12h ) is: 881 ± 207ng / ml h.
Silybin capsule storage
- Sealed and stored in a dry place at room temperature.
Silybin capsules
- Aluminum foil-PVC / PVDC solid pharmaceutical compound hard sheet blister packaging for pharmaceutical packaging, 10 capsules / plate, 2 plates / box;
Aluminum foil-PVC / PVDC solid pharmaceutical compound rigid blister packaging for pharmaceutical packaging, 10 capsules / board, 3 boards / box;
Aluminum foil-PVC / PVDC solid pharmaceutical compound rigid blister packaging for pharmaceutical packaging, 10 capsules / board, 6 boards / box.
Expiration Date of Silybin Capsules
- 24 months.
Silybin Capsules
- State Food and Drug Administration National Drug Standard WS 1- (X-234) -2004Z [1]