What is Renin's antagonist?

Antagonist Renin is a compound that inhibits the secretion of renina from the kidneys. Renin, the enzyme, is a key part of the Renin-English system (RAS), a system used by the human body to regulate blood pressure. Pharmaceutical companies use Renin antagonists in drugs for the treatment of hypertension, a condition caused by overproduction of renin, which leads to high blood pressure. A similar type of drugs known to the inhibitors of the converting angiotensin (ACE) enzyme (ACE) also interrupts RAS, although they do not particularly affect Renin.

kidneys and renin they produce help to maintain normal blood pressure. The kidneys are either maintained or released by water and salts. Renin, when it is made, acts on the body to create a temporary increase in blood pressure. This action is a key function in the response of the "fight or flight" of the body. Yet when hypertension occurs, the body produces too much renin; Blood pressure remains high.

hypertension can have many negative long -term effects of the body. Chances of a heart attack and stroke are rising,Especially if an individual has an existing state, such as diabetes. Another possibility is kidney failure because high blood pressure burden the kidneys. Although a number of lifestyle changes can help relieve hypertension, antagonist Renin stops hypertension in his source: Renin's production.

Although treatment for the treatment of hypertension has existed for many years, drugs based on Renin antagonist have only been available since 2007. Aliskiren was the first Renin inhibitor approved for human use. Aliskiren and drugs, as if they had focused on the juxtaglomerular kidney cells, those responsible for renina secretion. One dose is effective for 24 hours. Since the summer of 2011, no medical evidence has shown that Aliskiren or other newer Renin antagonists have no negative effects on the kidneys.

Medicana hypertension Based on Renin antagonists, they are not the only ones that affect races. Drugs known as inhibitorsACE also affects races, albeit in another place in the races cycle. Although antagonist Renin completely prevents races from running, ACE inhibitors interrupt the halfway process. Compound angiotensin I is unable to convert to angiotensin II due to ACE inhibitor.

The overall effect of both types of drugs is the same. Because ACE inhibitors have existed longer than Renin antagonists, the medical community better understands their side effects and drug interactions. Individuals who are considering using Renin antagonists should consult with their doctors, as Renin antagonists may also apply to the same side effects and drug interactions of ACE inhibitors.