What Is Prodine?

Proline (Proline, abbreviated as Pro or P), -imino acid, neutral, isoelectric point is 6.30, solubility in water is greater than any amino acid, soluble in 162 g of 100 g of water at 25 ° C. Deliquescence is not easy to crystallize, and has a sweet taste. Co-heat with ninhydrin solution to form a yellow compound. Once entering the peptide chain, hydroxylation can occur to form 4-hydroxyproline, which is an important component of animal collagen. Hydroxyproline is also found in a variety of plant proteins, and is particularly involved in the formation of cell walls. Plants often have significant accumulation of proline under various stresses such as drought, high temperature, low temperature, and salting. It has been widely used in clinical, biological materials, industry, etc. ^[1] .

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Glutamate generates glutamate phosphate (-GP) under the action of glutamyl kinase (-GK), and then generates glutamate semialdehyde (GSA) under the action of glutamate semialdehyde dehydrogenase (GSADH) ), GSA spontaneously cyclizes to pyrroline-5-carboxylic acid (P5C), and is reduced to proline by the action of pyrroline-5-carboxylic acid reductase (P5CR).
Proline degradation in plants is basically the reverse of the synthetic process. This process first occurs in mitochondria. Proline is catalyzed by proline dehydrogenase (ProDH) in mitochondria to generate P5C. Lin-5-carboxylic acid dehydrogenase (P5CDH) generates glutamic acid. When the plant is subjected to osmotic stress, the process of oxidative degradation is inhibited, so that the proline content in the cell increases, and the plant rehydrates. This process will again Is induced, resulting in a decrease in proline content.

first-aid

[Ingestion] If the victim is awake and alert, give 2-4 cupfuls of milk or water. Seek medical attention immediately.

[Inhalation] Immediately from the scene to a place with fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical help.

[Skin] For at least 15 minutes, wash skin with plenty of soap and water, and remove contaminated clothes and shoes. If irritation develops or persists, seek medical assistance.

[Eye] Rinse the eyes immediately, rinse with plenty of water for at least 15 minutes, and raise the upper and lower eyelids from time to time. Get medical help.

deal with

[Treatment] Wash thoroughly after operation. Use with adequate ventilation. Reduce dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.

Hazard identification

[Inhalation] The toxicological properties of this substance have not been fully investigated.

[Skin] Low risk, normal industrial treatment.

[Eye] No irritation or other potential effects were found. Contact may cause transient eye irritation.

[Ingestion] The toxicological properties of this substance have not been fully investigated.

Exposure control / personal protection

[Personal protection] Eyes: Wear appropriate protective glasses or chemical safety goggles, OSHA's Eye and Face Protection Regulations 29 CFR 1910.133 or European Standard EN166. Skin: Wear suitable protective gloves to prevent skin contact. Clothing: Wear appropriate protective clothing to prevent skin contact.

[Respirator] According to OSHA respirator regulations 29CFR 1910.134 or European standard EN 149. Always use a NIOSH or European standard EN 149 approved respirator if necessary.

[Effect of exposure] May irritate eyes, skin and respiratory tract. Expected to be a low ingestion hazard.

Fire-fighting measures.

[Flash point] 106

[Fire extinguishing] Wear self-contained breathing apparatus, MSHA / NIOSH (or equivalent), and full body protective clothing under pressure. Sufficient dust concentrations can form explosive mixtures with air. Combustion produces toxic gases. Extinguishing media: Low fire, use water spray, dry chemical powder, carbon dioxide or chemical foam. Use the most suitable extinguishing agent.

Accidental release measures

[Small leak / leak] Sweep it off and put it in a suitable container for disposal. Avoid creating dusty conditions. Provide good ventilation.

Stability and reactivity

Sale Number 31

[Stability] Stable at normal temperature and pressure.

[Incompatibility] Strong oxidant.

[Decomposition] nitrogen oxides, carbon monoxide, carbon dioxide.

Storage and transportation characteristics

[Storage] Store in a cool, dry, well-ventilated place away from incompatible materials.

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