What factors affect Renin levels?
The main factors that affect renin levels are blood pressure, the amount of sodium in the body and triggers from the sympathetic nervous system. There is a sensitive feedback mechanism that allows the amount of renin to rise or down according to these triggers. Renin is an enzyme that plays a major role in a complex system of hormones and enzymes in the human body called the Renin-English system (RAS). It controls different functions in the body, including blood and blood pressure.
produced by specific renal cells in the kidneys that are activated by these triggers, renin levels increase or decrease. When they increase, the cascade of reactions occurs in the body through many other enzymes and hormones, which eventually causes an increase in blood pressure. This is achieved by various mechanisms, including vasoconstriction of blood vessels and increased thirst, causing increased fluid intake.
sodium levels will increase reninorate. Low sodium or hyponatraemia may be caused by various factors, including drinking too much water, age and some medicines. Conversely, high sodium levels will cause renin levels to reduce and have the opposite effect.
When the blood pressure of the body decreases, receptors that are sensitive to pressure send the renal cells to increase renin levels. This causes the whole cascade to appear and increase blood pressure again. The sympathetic nervous system of the body is simply put, a system that controls most of the internal organs in stressful situations. Runs from this generally involuntary system may affect renin levels.
Many therapeutic drugs relies on the renin-English system for its action. The relatively new class of drugs to reduce blood pressure that acts directly on renin levels is renin inhibitors such as aliskiren. Pills such as blood pressure Jakolisinopril or Enlapril, which are ACE inhibitors, lower blood pressure action on the races system further aftercascade.
Renin levels can use physicians during the diagnosis of hypertension along with various other tests. It is a simple blood test performed by the laboratory and helps a medicinal physician to determine which antihypertensive is best for a particular patient. Renin's blood test is often performed in combination with aldosterone test.
Maintenance of stable Renin levels in the body is essential. This allows the body to maintain a healthy volume of blood and blood pressure. Regular monitoring of blood pressure is recommended, especially in people with a family history of hypertension and growing age.