What Is Involved in Frontal Lobe Development?

Children's craniofacial deformity syndrome (Hallermann-Streiffsyndrome), also known as HS syndrome, lower jaw, eyes, face, skull dysplasia syndrome, lower jaw, eyes, face, skull hypoplasia, dyscephaliaoculomandibularis-hypotrichosissyndrome, Head-face mandible and eye deformity syndrome, congenital cataract bird face deformity syndrome, congenital cataract and thin hair syndrome (cataractacongenitahypotrichosissyndrome), Ullrieh-Fremety-Dohna syndrome, Francois syndrome, Audry syndrome type I, Fremery- Donhna syndrome and others. The symptoms are characterized by head and face deformities, congenital cataracts, and thin hair. This disease is often accompanied by other deformities, such as spinal deformity, osteoporosis, symmetry dwarf, mental retardation, etc.

Craniofacial deformity

Children's craniofacial deformity syndrome (Hallermann-Streiffsyndrome), also known as HS syndrome, lower jaw, eyes, face, skull dysplasia syndrome, lower jaw, eyes, face, skull hypoplasia, dyscephaliaoculomandibularis-hypotrichosissyndrome Head-face mandible and eye deformity syndrome, congenital cataract bird face deformity syndrome, congenital cataract and thin hair syndrome (cataractacongenitahypotrichosissyndrome), Ullrieh-Fremety-Dohna syndrome, Francois syndrome, Audry syndrome type 1, Fremery- Donhna syndrome and others. The symptoms are characterized by head and face deformities, congenital cataracts, and thin hair. This disease is often accompanied by other deformities, such as spinal deformity, osteoporosis, symmetry dwarf, mental retardation, etc.

TCM disease name

Craniofacial deformity

Common locations

(I) Causes of Onset

The cause of the disease is unknown.

(Two) pathogenesis

Craniofacial deformity syndrome may be

1. Malformed head and face malformations are born with deformities such as scaphoid, triangular head, short head, etc. Some may have open cardia, sagittal and herringbone fissures, and brain hypoplasia, small facial features, narrow nose, small nose, small The jaw, cleft palate is small, and the ears are abnormal, so it is also known as bird face deformity syndrome.

2. Ocular malformation is a characteristic lesion of congenital cataract, which is mostly bilateral, and can be spontaneously ruptured and absorbed. There may also be no lens. Secondly, strabismus, nystagmus, small eyeballs, small cornea, blue sclera, iris defect, macular degeneration, etc. can occur.

3. Hair and skin abnormal eyebrows, eyelashes, armpit hair, pubic hair, etc. are thin and absent, pillow, forehead baldness. Sclerosing atrophic skin changes can occur, often with skin atrophy and roughness, and white spot disease, vitiligo, etc. can also occur.

The symptoms are diagnosed according to the three major characteristics of craniofacial deformity, congenital cataract, and thinning of hair. Routine laboratory tests generally have no specific findings. X-ray, B-ultrasound and brain CT should be done. X-ray film showed that the mandibular joint was displaced forward (obviously up to 2cm), the sparse bone of the mandible, and the condyle disappeared completely.

The symptoms must be related to

Refer to the prevention of congenital diseases. Prevention should extend from pre-pregnancy to pre-natal:

1. Premarital medical examination plays a positive role in preventing birth defects. The size depends on the inspection items and content, mainly including serological tests (such as hepatitis B virus, Treponema pallidum, HIV), and reproductive system tests (such as screening for cervical inflammation). , General physical examination (such as blood pressure, electrocardiogram) and asking family history of the disease, personal past medical history, etc., to do a good job of genetic disease consultation.

2. Pregnant women should avoid harmful factors as far as possible, including stay away from smoke, alcohol, drugs, radiation, pesticides, noise, volatile and harmful gases, toxic and harmful heavy metals, etc. In the process of antenatal care during pregnancy, systematic screening of birth defects is required, including regular ultrasound examinations, serological screening, etc., and chromosomal examinations if necessary.

Once abnormal results occur, it is necessary to determine whether to terminate the pregnancy; the safety of the fetus in the uterus; whether there are sequelae after birth, whether they can be treated, what to do afterwards, and so on. Take practical measures for diagnosis and treatment.