What Is a Platelet Factor?

Platelet factor (PF) is a specific substance contained in platelets. There are now more than 10 species known. When blood vessels are damaged, platelets and collagen tissue contact and accumulate, platelets rupture, release PF, and thus participate in the process of coagulation and hemostasis.

Platelet factor

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Platelet factor (PF), ie

Platelet factor (PF), ie

• PF ₁ , also known as "Coagulation factor (same as Plasma Factor V), has the effect of accelerating the conversion of prothrombin into thrombin;

• PF ₂ , also known as "Fibrinogen Activating Factor" (Thromboplastic material), has the effect of accelerating the conversion of fibrinogen into fibrin monomers;

• PF3, also known as "Platelet thromboplastin, cephalin, phospholipid", thromboplastin factor, phosphatidylserine, participates in the reaction of factors XIII, V and X, and together with these factors form thromboplastin;

• PF ₄ , also known as "Antiheparin factor", has antiheparin effect;

• PF ₅ , also known as "Fibrinogen coagulant factor" on the platelet surface, acts the same as fibrinogen;

• PF ₆ , also known as "antifibrinolytic factor" (glycoprotein, fibrinolysin, plasmin inhibitor), "antiplasmin", has an antifibrinolytic effect;

• PF ₇ , also known as "Platelet cothromboplastin, cothrom-boplastin, SPCA, proconvertin", can activate thromboplastin;

• PF ₈ , also known as "anti-thromboplastin", has antithrombin activity;

• PF ₉ , also known as "accelerated globulin stabilization factor" (same as Plasma Factor XIII), has the function of stabilizing acceleration globulin;

• PF ₁₀ , also known as "serotonin" and "5-hydroxytryptamine" (5-HT), has vasoconstrictive effect;

• PF ₁₁ , also known as "adenosine diphosphate" (ADP), can cause adhesion and accumulation between platelets.