What Is Ariboflavinosis?
Vitamin B 2 is also known as riboflavin. Riboflavin is absorbed by the human body through the intestinal tract, stored in the liver, and excreted or reabsorbed by the kidneys. Riboflavin is one of the important substances that promote redox in somatic cells. It also participates in the metabolism of sugar, protein, and fat in the body, and has the function of maintaining normal visual function. When the human body lacks riboflavin, especially when it is severely deficient, it may easily lead to dysregulation of cells in the mucosal layer of the human cavity and cause mucosal lesions. The specific manifestations are thinning of the mucosa, damage of the mucosal layer, and rupture of microvessels, followed by angular cheilitis, eye and face Inflammation, conjunctivitis, cheilitis, glossitis, mouth ulcers, dry ear and nose mucosa, dry skin and desquamation.
- English name
- vitamin B2 deficiency
- Visiting department
- Nutrition
- Common causes
- Increased body demand, poor eating habits, etc.
- Common symptoms
- Mucosa thinning, mucosal layer damage, microvascular rupture, etc.
Basic Information
Causes of Vitamin B2 Deficiency
- Increase in demand
- The body's demand for various nutrients, including vitamin B 2 , is increasing.
- 2. Bad eating habits
- The main sources of vitamin B 2 are fresh vegetables, soy products, and animal viscera, muscle and eggs, milk and other foods. Patients' poor dietary habits lead to a significant deficiency in the intake of various vitamins, especially the lack of vitamin B 2 intake.
- 3. Cooking methods and eating methods are not scientific
- It destroys the original vitamins in food and makes its intake relatively reduced.
Clinical manifestations of vitamin B2 deficiency
- Angular cheilitis
- Also known as angular sores. At the beginning, the corners of the mouth are wet, white, and eroded, and cracks gradually occur. The crack extends from the mouth angle to the side up to 1cm, seen on one side or both sides, but the side is heavier. The fissured epidermis peels off, forming ulcers, often with yellow or yellow-black scabs, and bleeding easily when opened. Oral ulcers in older children become chronic and dark brown pigmentation is common at the junction with the skin.
- Cheilitis
- The entire mucosa of the upper and lower lip can be bright crimson, and the longitudinal cracks of the lips increase. Sometimes the mouth is opened or the tears bleed when they cry. Sporadic blood vessels were seen along the junction of the mucosa and the skin. Such lesions are more severe in the lower lip, and each time there is a narrow scar after recovery.
- 3. Glossitis
- The surface of the tongue is smooth and bright magenta. Under strong sunlight, it can be microscopic blue in red. In the case of glossitis, there is a mushroom-shaped nipple and a contoured milk hypertrophy at the back of the tongue in the early stage, and then it shrinks, disappears, and the nipples become flat. The middle of the tongue is red with atrophy and cracks.
- 4. Angioproliferative conjunctivitis
- In the edge of the cornea within 1-2 days, many capillaries can be seen forming ring keratitis. One or two small white blister can also appear on the edge of the cornea, and then there is photophobia, tearing, burning or itching. When the disease progresses, the proliferated capillaries can invade the entire cornea, so that the cornea becomes cloudy, ulcers occur, and irisitis occurs. The edge of the face is also inflamed.
- 5. Seborrheic Dermatitis
- Occurred at the junction of the nose and lips, nose wings, behind the ears, forehead, eyebrows and other sebaceous glands. At the beginning, sebum overflowed as filamentous sebum, stuffed in the mouth of the sebaceous glands, high above the skin surface, and mostly formed in the palate, yellow and white desquamation was visible, and red spots were seen in the skinfold after wiping off.
Vitamin B2 deficiency diagnosis
- If diarrhea is severe and dehydration occurs, blood biochemical examination is performed. Serum niacin levels can be determined when possible, combined with clinical manifestations to confirm the diagnosis.
Differential diagnosis of vitamin B2 deficiency
- When diagnosing a vitamin B 2 deficiency, other vitamin deficiencies should also be considered. Special attention should be paid to niacin deficiency. Its skin symptoms are more common in areas exposed to sunlight or easy rubbing, such as the back of the hands and face, while vitamin B 2 deficiency starts at the junction of the nose and lips. The former is dermatitis and the latter is filamentous seborrhea, which should be distinguished.
Vitamin B2 deficiency treatment
- Oral vitamin B 2 , symptoms mostly disappeared in about 2 weeks. When the effect is slow, it can be changed to intramuscular injection. Also improve your diet and give multivitamin B tablets.