What Is Infant Botulism?

Clostridium botulinum food poisoning, also known as botulism, is a toxic disease caused by eating foods containing botulinum exotoxin. Clinically, nausea, vomiting, and central nervous system symptoms such as paralysis of the eye muscles and pharyngeal muscles are the main manifestations. If the rescue is not timely, the case fatality rate is high. Although this disease is rare, botulinum toxin has strong virulence and can be produced in large quantities. It can be poisoned by aerosol. The enemy may be used as a biological weapon in wartime. Sudden infant death syndrome was found to be associated with botulinum toxin poisoning in 1976, and the mortality rate was very high.

Botox food poisoning

Clostridium botulinum food poisoning, also known as botulism, is a toxic disease caused by eating foods containing botulinum exotoxin. Clinically, nausea, vomiting, and central nervous system symptoms such as paralysis of the eye muscles and pharyngeal muscles are the main manifestations. If the rescue is not timely, the case fatality rate is high. Although this disease is rare, botulinum toxin has strong virulence and can be produced in large quantities. It can be poisoned by aerosol. The enemy may be used as a biological weapon in wartime. Sudden infant death syndrome was found to be associated with botulinum toxin poisoning in 1976, and the mortality rate was very high.

Western Medicine Name

Botox food poisoning

English name

clostridium botulinum food poisoning

Other name

Botulism

The main symptoms

Nausea, vomiting and central nervous system symptoms

1. Sources of infection Livestock, poultry and fish are the sources of infection. The bacterial spores are widely distributed in nature.

The incubation period is 12 to 36 hours, the shortest is 2 to 6 hours, and the elderly can reach 8 to 10 days. The larger the poisoning dose, the shorter the incubation period and the worse the condition.

Sudden onset, headache, dizziness, dizziness, fatigue, nausea, and vomiting at the beginning of the disease (e-type bacteria nausea and vomiting are heavy, type a bacteria and type b bacteria are light); later, the inner and outer muscles are paralyzed and the eyes appear Symptoms such as blurred vision, diplopia, drooping eyelids, dilated pupils, and reflection of light disappear. Flushing of the mouth and pharynx, accompanied by sore throat, such as paralysis of the pharyngeal muscles, can cause breathing difficulties. Muscle weakness is mainly seen in the neck and proximal limbs. Due to the weakness of the neck muscles, the head tilts forward or leans to one side. Tendon reflexes can be weakened symmetrically.

Autonomic nerve endings are excited first and then suppressed, so

(1) Have a history of eating suspicious food, especially ham, sausage, canned or bottled food, and people with meals have a collective illness.

(2) There are special neurological symptoms and signs, such as diplopia, strabismus, drooping eyelids, difficulty swallowing, and difficulty breathing.

(3) The animal test can be used to check the botulinum toxin in the serum and suspicious food of the patient, and the suspicious food can be used for anaerobic culture to isolate pathogenic bacteria. In a war environment, the enemy must be wary of casting aerosols containing botulinum toxins; if in doubt, the aerosols can be washed from the attachment for animal testing.

Animal tests:

(1) Take early serum and inject it into mice (or

(1) Antitoxin treatment of polyvalent botulinum toxin (types a, b, and e) has specific effects on this disease and must be applied as soon as possible. The injection is most effective within 24 hours after onset or before paralysis occurs. The dose is 50,000 to 100,000 units each time. Intravenous or intramuscular injection (serosensitivity test first, desensitization treatment for allergic patients), if necessary, repeat the same dose 6 times later. If the type of bacteria has been determined, the same type of antitoxin should be injected, 10,000 to 20,000 units each time. If the course of the disease has passed for two days, the antitoxin effect is poor, but the injection should be continued to neutralize the residual toxins in the blood.

(2) Patients treated symptomatically should be bedridden strictly and given appropriate sedatives to avoid exacerbation of paralysis. Patients can use 5% within 4h after eating

Strict management and inspection of food, especially the preparation and preservation of canned food, ham and pickled food. If the ends of food cans are bulging, or the content and flavor are changed, they should be prohibited from selling and consuming, even if they are boiled. Cereals and beans may also be contaminated with botulinum, so it is forbidden to eat fermented or spoiled food.

In the case of war, precautions should be taken to prevent the aerosol spreading botulinum toxin from contaminating drinking water and causing collective poisoning.

In the case of botulinum poisoning in the same food, the remaining personnel should be immediately given multivalent refined botulinum antisera for prevention, subcutaneous injection of 1000 ~ 2000u, once a week for a total of 3 times. Those who eat canned food regularly may consider botulinum toxin injection. ^[1]