What Is Tardive Dyskinesia?

Tardive dyskinesia (tardive ADHD) is a special and lasting extrapyramidal reaction that is mainly seen in patients who take large doses of antipsychotics for a long time (more than 1 year). It is most likely to occur after reduction or withdrawal After long-term use of drugs to block the striatum dopaminergic receptors, the latter is caused by hypersensitivity, and may also be related to impaired GABA function in the basal ganglia.

Tardive dyskinesia

Tardive dyskinesia (Tardy ADHD) is a special and lasting
Neurology
Tardive ADHD
At present, there is no relevant epidemiological survey data in the literature. It is reported in the literature as 5% to 57%. Casey et al. Think that 13.9%. Kane found
The disease is abnormal dance-hands and feet
More common in
1. Occurs in old age
1. The focus of this disease is on prevention, taking
The first is to avoid risk factors. Clinicians should
The disease mostly occurs in the elderly, especially women, especially in the elderly with cerebral organic lesions, and often the symptoms are more severe, the recovery is slower, and people with emotional disorders are also prone to occur. All kinds of antipsychotic drugs can be caused, and the antipsychotic drugs containing fluorine elements such as fluphenazine, triflurazine and droperidol are more common. Most of them take antipsychotic drugs for more than 1 to 2 years. The shortest is 3 months and the longest is 13 years.
1. Add medicine as slowly as possible, and avoid long-term or large-dose application of antipsychotics;
2. Avoid the combined application of two or more antipsychotic drugs;
3. Minimize or not use anti-Parkinson's drugs; when stopping or changing antipsychotics, you should gradually reduce the dose, rather than abruptly stop the drug;
4. Those who are old or frail or with organic pathological changes should be given the lowest dose; anticholinergic drugs should not be used or should be used less often if not necessary;
5. Early detection and early treatment. Once symptoms occur, reduce the amount of antipsychotic drugs or switch to other drugs, and discontinue the drugs if necessary.

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