What Are Atherogenic Lipoproteins?
Lipoprotein (lipoprotein) is a type of spherical microparticles composed of a hydrophobic core rich in sterol lipids and triglycerides and a shell composed of proteins, phospholipids, cholesterol, and the like. Lipoproteins play an important role in the packaging, storage, transportation, and metabolism of extracellular lipids in insects and mammals. Abnormal lipoprotein metabolism (usually accompanied by changes in lipid and protein components) and arteriosclerosis, diabetes, Obesity and tumorigenesis are closely related.
- Lipoprotein (lipoprotein) is a type of spherical microparticles composed of a hydrophobic core rich in sterol lipids and triglycerides and a shell composed of proteins, phospholipids, cholesterol, and the like. Lipoproteins play an important role in the packaging, storage, transportation, and metabolism of extracellular lipids in insects and mammals. Abnormal lipoprotein metabolism (usually accompanied by changes in lipid and protein components) and arteriosclerosis, diabetes, Obesity and tumorigenesis are closely related.
- The core component of lipoproteins is triglycerides, which are surrounded by a layer of phospholipids, cholesterol, and protein molecules.
- Lipoprotein is a carrier of insoluble lipids in blood, and a lipid-protein complex formed by combining insoluble lipids and proteins in blood. There is no covalent bond between lipids and proteins in lipoproteins, and most of them are bound by hydrophobic interactions between the non-polar portion of the lipid and the protein components. Usually using dissolution characteristics,
- Lipoproteins can be classified according to their density: chylomicrons (CM), very lowdensity lipoproteins (VLDL), intermediate density lipoproteins (IDL), and low density lipoproteins , LDL) and high density lipoproteins (HDL).
- To
- In layman's terms, fat in the blood depends on the carrying and binding of proteins. The combination of fat and protein is
- due to
- At present, clinical diagnosis mainly uses high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and total cholesterol as the detection indicators of whether the level of lipoprotein is normal. High levels of low-density lipoprotein cholesterol are generally considered to be a major risk factor for myocardial infarction and sudden death, while low levels of high-density lipoprotein cholesterol increase the risk of cardiovascular disease.
|
|
|
|
|
|
|
|