What are the interactions between amoxicillin and acetaminophene?

Because the liver metabolizes amoxicillin and acetaminophen, there is a possibility that both could damage the health of the liver. This interaction exists despite the fact that from a pharmacological point of view there is no direct interaction between drugs. The main problem is the possible interactions of acetaminophene that can occur if the drug is used in significant doses for a long time. In addition, both drugs may have negative reactions with some other medicines such as warfarin.

amoxicillin and acetaminophen are not available in a combined dose. Amoxicillin is a popular antibiotic for a prescription used to treat bacterial infections such as ear and gonorrhea infections. Doctors often recommend over -the -counter acetaminofen to those who use amoxicillin to reduce pain or fever associated with infection. For most people, the use of both drugs is not a reason for concern at the same time.

Amoxicillin and acetaminophen are among the hundreds of drugs that are in order to be able to cause liver damage. By using these drugs in the sameThere is a possibility of increased risk of hepatotoxicity, chemically caused by liver damage, occurs. Weakness, nausea and abdominal pain are probably symptoms of hepatotoxicity. In fact, acetaminophene is one hand with more cases of liver damage than any other medicine. Other symptoms of toxicity may include diarrhea, nausea and fatigue, all of which can easily be released or associated with a number of other conditions.

It seems that hepatotoxicity associated with amoxicillin and acetaminophene is an unusual occurrence. If both drugs are indicated by hepatotoxicity, it is usually because the patient has different risk factors that make the liver more susceptible to damage. For example, severe alcohol use can also damage the liver.

cases of liver toxicity including this combination of drugs seems to be associated mainly with excessively overcoming therapeutic recommendations for dosing acetaminophene. MedicineThe pain relief is found in various doses, strengths and brands of over -the -counter and prescription drugs. Consumption of drugs from multiple sources such as extra pain relief and liquid influenza drugs can lead to overdose sufficiently high to affect the normal functioning of the liver.

unfavorable interactions including amoxicillin and acetaminophene are also more likely if they are taken with other drugs known to cause interactions such as warfarin. Warfarin is a thinner of blood that is used to prevent blood clots; However, the ability to control bleeding can be affected by relief of pain or antibiotics. While patients may have to regularly have tests of international normalized ratio (INR) on these warfarin drugs to measure how blood is needed and doses.

Although most individuals seem to be able to make amoxicillin and acetaminophen together in the short term without any problem, the risk possibleCancer should be taken seriously. To avoid injury, health workers warn patients to adhere to the dosage recommendations. At the risk of encountering acetaminophene from multiple sources, patients also invite to carefully monitor all sources of pain lighteners, remain in the appropriate daily dosage instructions and prevent long -term reliance.