What are the medical use of prostaglandins?
The effects of prostaglandins on smooth muscle allow the use of hormone to treat glaucoma and certain ischemic disorders. Prostaglandins, which consist of unsaturated fatty acids, regulate the ion flow at the cellular level and can be used as an induction of work. Non -steroidal anti -inflammatory drugs usually act as antagonists of prostaglandin to reduce fever, inflammation and pain. These actions also often produce gastrointestinal disorders. The use of prostaglandins in parallel with NSAIDs reduces possible stomach adverse reactions. Drugs are generally prescribed for the action against intraocular pressure commonly associated with open angle glaucoma. Prostaglandin analogs in formulation effectively increase Uveoscleral drainage and reduce pressure. When administered intravenously, individuals suffering from ischemic disorder that include Reynaud's syndrome experience less and less frequent attacks. The effects of vasodilation, produced by relaxation of prostaglandins of smooth muscles, increase blood flow and reduce the symptoms of SPOJené with ischemia.
doctors can use PGE1 or Alprostadil to maintain the opening of Ductus arteriosis in infants diagnosed with these conditions related to the heart until surgery. Ductus generally allows blood flow from the pulmonary artery to bypass the lungs and travel back to the aorta in unborn infants. This valve usually closes shortly after birth, but can produce stress in infants suffering from heart or pulmonary anomalies. Maintaining this hole reduces the workload and bypasses defective blood vessels.
men who experience erectile dysfunction can also receive recipes for Alprostadil. Because drugs usually release arterial smooth muscles, blood flow to the penis increases. With adequate or increased blood flow, men generally achieve erection. Medicines can be injected directly into penile cavernosa or inserted in the pellet mold until the uric uric figure is opened.
administered vaginally in the form of a gel or suppository form, the drug of dinoprostone usually causes work. Prostaglandin hormones, known as PGE2, release the fibers of the smooth muscles of the uterus, which ripens the uterus by causing dilation and thinning. Preparation also usually initiates uterine contractions. Birth physicians can also use PGE2 after delivery to maintain the uterine tone. When the uterus loses a tone or the ability to download properly, blood flow increases, which can cause bleeding.
NSAIDs generally inhibit the effects of prostaglandins. Some of these effects normally protect the sensitive lining of the gastrointestinal tract. Minus these protective properties may be ulceration. Misoprostol is a prostaglandin analogue that increases the production of bicarbonate and mucus. Increased mucosal protection reduces the likelihood of internal NSAID damage.