What Is a Randomized Clinical Trial?
Evidence-based medicine is a new model of modern clinical practice and research, and it is also a new direction for the development of international clinical medicine. The advent of evidence-based medicine has revolutionized clinical medicine and completely changed the basic concepts of clinical medicine.
Randomized controlled clinical trial
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- Chinese name
- Randomized controlled clinical trial
- Foreign name
- evidencebasedmedicine
- Nature
- New model of modern clinical medical practice and research
- Category
- test
- Evidence-based medicine is a new model of modern clinical practice and research, and it is also a new direction for the development of international clinical medicine. The advent of evidence-based medicine has revolutionized clinical medicine and completely changed the basic concepts of clinical medicine.
- David Sackett, the main founder of evidence-based medicine and an internationally renowned clinical epidemiologist, once defined evidence-based medicine as "carefully, accurately and wisely applying the best research evidence available to determine patient treatment." Based on this definition, evidence-based medicine requires clinicians to carefully, clearly and reasonably apply the best available evidence to determine the medical treatment of specific patients, make accurate diagnosis, choose the best treatment method, and strive for the best results and prognosis. .
Recently, Professor Sackett himself revised the definition of evidence-based medicine to make it more comprehensive and more convincing. The latest definition of evidence-based medicine is: "Prudent, accurate and wise application of the best research evidence currently available, combined with the individual professional skills and long-term clinical experience of the clinician, taking into account the values and wishes of the patient, perfectly combining the three Together, work out a specific treatment plan. " Obviously, modern evidence-based medicine requires clinicians to work hard to find and obtain the best research evidence, and to combine personal expertise, including pathophysiology of disease occurrence and evolution, and personal clinical work experience, combined with others (including experts) Observations and research results; not only must follow the laws and needs of medical practice, but also according to the "patient first" principle, respect the patient's personal wishes and practical possibilities, and then make diagnostic and treatment decisions. The core idea of evidence-based medicine is to combine clinical evidence, personal experience and the actual condition and willingness of patients in medical decision-making.
The clinical evidence mainly comes from randomized controlled clinical trials (RCT) and systematic reviews or meta-analysis of large samples.