What is Acyclovir?

Acyklovir is an antiviral drug that is often prescribed in the fight against various Herpes virus strains, especially the Herpes simplex type I (HSV-1) virus. Since the raw crystalline powder has a lengthy chemical name 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy) methyl] -6H-Purin-6-one, is most often referred to as acycloguanosine in clinical environments. However, it is launched as pharmaceutical under trade names Cyclovir, Acivir, Zovirax and Herpex, with Acyklovir recognized as a standard international proprietary name for this medicine. However, it can also be given by a 25 mg/ml concentration with immunosuppressed patients who are infected with Varicella-Zoster, a virus that causes chickenpox in children and shingles in adults. Acyclovir is also formulated in topical creams for the treatment of herpes simplex focusing mouth or genitals. In addition, the drug is available as eye ointment or decreases to a three percent concentration to treat corneal keratitis.

The ability of this drug to inhibit the replication of the virus is due to the fact that it is highly selective to thymidine kinase, the enzyme "programmed" Herpes Simplex and Varicella-Zoster. This promotes the chain of enzymatic reactions and phosphorylation to bring the acyclovir to the acyclovir monophosphate and finally into the acyclovirus triphosphate. Antiviral activity caused by these events can be observed both in vitro and in vivo , which means outside and inside the body. In addition, the acyclovir is pricking, which means that it becomes active when introduced into the body in inactive form and subsequently metabolized. This is happiness because the drug is poorly absorbed.

While acyclovir is well tolerated by most individuals, certain side effects with its use, most commonly nausea, headache and diarrhea have been reported. Serious complications or allergic reactions are rare, but medicines should be interrupted immediately ifThere will be disorders of visual visuals or hallucinations, as well as seizure, increased heart rhythm, stressed breathing or swelling of the face or tongue. Acyclovir should not be used during pregnancy or nursing, as it is known that the drug is connected to DNA and passes into breast milk. In addition, acyclovir reacts with some muscle relaxants and drugs to treat DNA, namely tizanidin (Zanaflex) and Probenecid (Benuryl). Because this medicine crystallizes in the kidneys, there may be a risk of kidney damage after very high doses of injection.