What is clioquinol?

Clioquinol, whose complete chemical name is iodochlorhydroxyquin , is a drug used to treat mold and protozoan infection. It works by blocking certain enzymes that are responsible for DNA replication, and thus by stopping any mushroom or protozoan, as in the case of Amebical dysentery, in growth. If it is used internally in large doses, this may cause damage to the nervous system tissues.

Clioquinol is largely used locally. It is often combined with hydrocortisonic cream to treat skin infections. This drug can help provide relief from itching, redness and the overall discomfort that these types of infections produce. In some countries, the drug has been largely interrupted, or at least seriously limited as a result of the outbreak of myelooptic neuropathy Subacture in Japan. It has been estimated that somewhere between 10,000 and 30,000 people counterbatho disease during the outbreak that caused paralysis, blindness and even death during the twenty -year period from the middle of the fifties to Plead 70 years. In 1978, the Tokyo Court ruled that Clioquinol was responsible for the epidemic.

There was no definitive explanation of why Clioquinol caused Smon, which led to the fact that it was another factor that contributed to the high occurrence of the disease. One particular argument was that it was used 20 years before the outbreak. There are many theories about the cause, including the wrong dose, interaction with another compound and interaction with another virus.

Despite the controversy surrounding Clioquinol, interest has been revived, especially for its possible role in the prevention of neurodegenerative diseases. It turned out that it will stop the progression of Alzheimer's disease in a vclinical study. Scientists believe that the medicine will stop progression because cheete zinc and copper ions help. There was also positive results in help with Huntington's disease. Other studies were carried out on animals onMcGill University in Canada, which showed that it could reverse the progression not only about Huntington and Alzheimer's disease, but also the Parkinson.

It is currently produced in different countries around the world. Denmark used it for protozoan infections. The US used it indirectly in that the Australian company has the rights to produce a drug for use in this country, especially for use with Alzheimer's disease. It is also made in India, especially for current use.