What is Glyburide?

Glyburide is a drug that is used to treat type II diabetes. Je to ve třídě sulfonylmočoviny anti-diabetických léků. There are problems with this compound that it can cause blood sugar levels to be dangerously low, a condition known as hypoglycaemia. This medicine, which is also known as glibenlamide, is often prescribed with metformin anti-diabetic drugs in a combination commonly known as glucovance®. They all have a similar way of effect. These compounds act on the pancreas to increase the amount of insulin relaxed. Glyburide is a type of second generation of Sulphonylurea and has less side effects in this class than earlier medicines. In general, one thinks that diabetes is a problem of blood sugar, which is too high, known as hyperglycemia. Hypoglycaemia can be life -threatening and cause coma and death. The study has proposed an increased risk of mortality due to the possibility of hypoglycaemia using this drug.

The advantage of Biguanide Anti-Diabetic drugs, such as widely used metformin, is that they do not tend to cause hypoglycaemia. Metformin is often combined with gloyburide in one pill, resulting in more effective treatment of type II diabetes. Both drugs have different ways of effect and work well in combination. There is some concern that this mixture may have dangerous side effects.

Glyburide is only effective in the treatment of type II diabetes. Most people with this type of disease can still produce insulin. Patients with type I diabetes are unable to produce insulin. Since the way of this drug is caused by an increase in insulin, it will not help people who are not at all.

There is great concern about whether drugs in sulphonylurea are safe to use during pregnancy to treat gestational diabetes. The fear was that they could cause congenital fetal defects. Newer research with gliburide indicated that it is safe to use during pregnancy. CrusThis is not the case of gestational diabetes in general until the second trimester. The drug would not be required during the first trimester, which is when most of the effects of drugs that cause mutation show their effects.