What Is Propoxyphene?

Propoxyphene, also known as dextropropoxyphene, is one of the commonly used opioid analgesics. It is used to treat mild to moderate pain. Compared with other analgesics, dextropropoxyphene has a faster onset of action. Features.

Propoxyphenol

Propoxyphene, also known as dextropropoxyphene, is one of the commonly used opioid analgesics. It is used to treat mild to moderate pain. Compared with other analgesics, dextropropoxyphene has a faster onset of action. Features.

Chinese name

Propoxyphenol

Foreign name

dextropropoxyphene

Alias

Dextropropoxyphene; dalfon; dalfon

Category

painkiller

First approved by the US Food and Drug Administration in 1957, the trade name of propoxyphene single formulation is Darvon, and the trade name of acetaminophen compound formulation is Darvocet.

Chinese name dexpropoxyfen

Chinese alias: dextropropoxyphene; dalfon; dalfon

English name: dextropropoxyphene

Chemical name: 4-Dimethylamino-3-methyl-1,2-diphenyl-2-butanol propionate

Structural formula:

1. Overdose of dexpropoxyphene will definitely cause adverse reactions, because dexpropoxyphene has a very strong analgesic effect, 32.5mg of dexpropoxyphene is equivalent to 3mg

At present (December 2010), propionol-containing medicines mainly include propoxyphene compound tablets, propoxyphene and compound tablets. As long as you follow the instructions of the medicine or take it under the guidance of a doctor, no overdose will occur, and no overdose will occur.

In December 2010, the US Food and Drug Administration (FDA acronym) announced its recommendation to stop using propoxyphenol painkillers, requiring manufacturers to consciously withdraw such drugs from the market.

The FDA states that large doses of propoxyphenol can cause difficulty swallowing, hallucinations, and toxic psychosis, and may cause respiratory depression. Acute overdose can produce multi-system symptoms such as spasms, hallucinations, insanity, and even coma, respiratory depression, apnea, tachycardia, high or low blood pressure, cardiac conduction disorders, and even cardiac arrest. The FDA has reported that 222 cases have a mortality rate of 8%, and has suggested that respiratory depression is more common in patients under 30 years of age, and cardiotoxicity is more common in the elderly.

It is understood that the propoxyphenol analgesics sold in the United States are mainly produced by the privately held Xano-dyne pharmaceutical company and are sold in the United States market under the brand names of Dalfont and Daltech. Currently (December 2010) the The company has agreed to stop selling both products altogether. ^[1]