What is the difference between tetracycline and doxycycline?

tetracycline and doxycycline are part of the class of broad -floor antibiotics known as tetracycline antibiotics. All antibiotics in this drug class are derived from the same basic structure of four hydrocarbon circles. However, each medicine varies slightly in terms of the exact structure of the ring, recommended use, pharmacokinetics and documented bacterial resistance. Doctors prescribe both these drugs for many of the same infections, but each drug has been proven more effective than others in some applications.

The primary difference between tetracycline and doxycycline lies in pharmacokinetics of every drug. Pharmacokinetics are simply how the body reacts or acts to certain medicines. This includes how the body distributes the medicine, metabolizes it and eventually eliminates it. To illustrate, tetracycline is metabolically concentrated in various body tissues that doxycycline. For example, doxycycline reaches the highest metabolic concentration C in the eyes, while tetracycline focuses primarily on body liquidIny. Such differences are both similar and for changing clinical or recommended use. Bacterial infections such as chlamydia, Lyme's disease and anthrax benefit from tetracycline or doxycycline treatment. As prophylactic or prevention against the spread of contagious bacterial infections such as malaria and bubonic plague, doxycycline is usually more effective. Some passengers are often prescribed doxycycline before traveling to areas known for malaria infections.

Recommendations for drug management, such as food or without food, water, dairy products and other measures, are directly related to pharmacokinetics. Management measures illustrate another difference between tetracycline and doxycycline. Specifically, it is known that antibiotics bind with food and minerals such as magnesium, calcium and iron. In accordance with this, patients are often advised to avoid a combination of certain foods or supplements with antibiotics to support better absorption.

Patients are usually recommended not to take tetracycline with food, dairy products, iron supplements or antacides. Alternatively, food -taking patients are allowed to take food drugs because it does not bind to proteins in the diet so easily. Measures such as avoiding iron or calcium, dairy products or antacids remain the same for both drugs.

In terms of discovery and use, tetracycline was introduced before doxycycline. Tetracycline, which was first derived from bacteria Streptomyces aureofacians, is considered a naturally occurring compound. Dooxycyline, on the other hand, is considered a semi -synthetic antibiotic. In response to the growing resistance of certain bacteria to antibiotics, scientists synthesized specific changes in the structure of the circle of other tetracycline antibiotics for doxycycline development. When comparing tetracycline and doxycycline, doxycycline has been shown to be more effective against resistant strainsH bacterial infections.