What is the relationship between corticosteroids and depression?
corticosteroids are steroid hormones. These hormones help relieve inflammation, allergic symptoms, asthma, skin conditions and other diseases. Clinical studies show the connection between corticosteroids and depression. Patients taking corticosteroid drugs may experience mild or severe depression, depending on the dose, the frequency of dose, other drugs and the patient's own sensitivity to the dose of corticosteroids. Depression and mood fluctuations are listed as some of the side effects of corticosteroids.
The grazed glands of the body naturally produce corticosteroids. The hormones are part of the combat or flight response made by the adrenal cortex. Natural corticosteroids control the fine chemical and physiological functions of the body, such as stress reactions, immune system, metabolism and others. Scientists have developed synthetic corticosteroid drugs to treat various diseases and their symptoms, as well as to provide supplements for people whose number of corticosteroids low.
correlation between corticosteroids and depression is widely knownBut it is not quite understood. Since 2011, scientists have not been able to determine the exact cause and severity of patient depression to the drug. Some patients experience euphoria while others suffer from mild to severe depression seizures. Corticosteroid patients are more susceptible to mood and depression fluctuations than patients. The amount of dosage and duration of the drug seems to determine the severity or prolongation of depression, but the study shows that depression is usually released when the drug dose is reduced or the regime is completely stopped.
The physiological side effects of corticosteroids and depression is therefore difficult to predict and treat. Some studies show that genetic abnormalities determine the level of depression, such as the position and function of neurotransmitters and the imbalance of chemicals produced by the brain, such as serotonin and dopamine, are genetic. Stress plays a big role in correlation between corticosteroids and depression. Events that can trigger an excrementYvy moods or depression, such as the birth of a child or the death of a loved one, are increased by the drug.
The most common use of corticosteroids is the treatment of inflammation, especially rheumatoid arthritis and inflammatory diseases of the skin, intestines and respiratory system. This medicine is available in the form of cream, aerosol and tablet. Betamethasone, hydrocortisone and budesonide treat the conditions of the skin and asthma in the form of cream or oral tablets. Cortison, dexamethasone, methylprednisolone, prednisolone and prednisone are usually taken in oral form for the treatment of arthritis, ulcerative colitis, psoriasis, allergies and lupus.