What are hematopoietic stem cells?
Hematopoietic stem cells (HSC) are cells that can produce all blood cells. It generates lymphocytes, granulocytes and red blood cells to achieve these HSCs. Lymphocytes and granulocytes are types of white blood cells. Hematopoietic stem cells create the necessary blood cells in this process. HSC also creates new stem cells.
HSC are usually placed in bones that contain marrows. They are also found in very small numbers in the blood and in large numbers in the umbilical umbilical cord blood. Stem cells, especially HSC, have the potential to replace damaged cells such as damaged bone marrow in the case of leukemia. No other type of stem cell is regularly used for therapy and transplantation like HSC. The stroke is responsible for production of up to 70% of the whole blood cell, as well as all plates. Plates are structures in the form of disks that allow blood clotting. They can also enter the bloodstream. HSC are also characterized by the ability to allow their own cell death or apoptosis if b is bUNA damaged or unnecessary.
HSC have been strongly studied since the 1950s and have been used in patients with immune system disorders, blood and cancer disorders since the 1960s. These cells can be implanted in other tissues and become other cells such as neurons. Although there is a great potential for these cells to be used in therapies for degenerative diseases, there are problems with their use.
stem cells, especially HSC, cannot replicate and distinguish themselves in an artificial environment such as a culture bowl or tube. TZE is also not a way to accurately identify a stem cell from other white blood cells. Hematopoietic stem cells tend to have the same size and shape as the same behavior as white blood cells.
Identification of these cells is further disturbed because there are two types of hematopoietic stem cells, long -termCH and precursor cells. Long -term cells can be restored for an indefinite period and are found in the bone marrow. Precorious cells, also called progenitor cells, can also be found in the bone marrow, but cannot be inflictly replicated. Long -term stem cells are much more advantageous for therapeutic purposes.
When a patient has leukemii-rank of bone marrow or other organs creating blood-timely, he receives as a treatment of allogenic transplantation of hematopoietic stem cells. The first step in such a procedure requires the patient to undergo radiation therapy to eradicate his own bone marrow and HSC. The donor's bone wood is then transplanted to Leukemia Patient. After it is implanted, the new HSC multiplies and distinguishes to replace cells that have been destroyed by radiation.