What Is an Angiotensin-Converting Enzyme?

Angiotensin converting enzyme (ACE) is also called kallikrein II or peptidyl-carboxypeptidase. It belongs to vascular endothelial cell membrane-binding enzyme. It cuts the amino acid into two segments from the C-terminus of the peptide, and can hydrolyze the C-terminal dipeptide residue of the peptide chain. ACE is widely distributed in various tissues of the human body, and is rich in epididymis, testis, and lung. Among them, pulmonary capillary endothelial cells have the highest ACE activity. Its attachment to the surface of endothelial cells can be interpreted into the blood circulation. ACE has two main functions: