What is an enzyme converting angiotensin?

The

enzyme converting angiotensin (ACE) is an enzyme that involves the conversion of angiotensin to angiotensin II. This leads to narrowing or opening of blood vessels, which is a process known as vasoconstriction. The enzyme of the converting angiotensin leads to a number of health conditions for which a certain category of drugs has been created. More specifically, it is an exopeptidase that catalyzes the ends of peptide or protein bonds to release individual amino acids. The enzyme converting angiotensin is released from cells that contain lungs and kidneys.

Angiotensin I, which comes from the kidneys, lacks any biological activity. This decapeptide - a peptide consisting of ten amino acids - existed as a precursor of angiotensin II, which is its active form. Angiotensin II is an octopeptide, which means it contains eight amino acids. ACE catalyzes the transformation of peptide bradykinin degradation is also responsible by the removal of two amino acid angiotensin I.

angiotensin-convertingHo the enzyme. It acts as a vasodilator that is an agent that extends blood vessels. Therefore, Bradykinin has the opposite effect of angiotensin II.

Two functions of the converting angiotensin are angiotensin converting the enzyme an important part of the Renin-English system (RAS). It is a hormonal system responsible for regulating blood pressure and balance of body fluids, collectively known as extracellular volume. Racs oversee the substances located outside the cells. "Renin" prefix refers to an enzyme that induces the production of angiotensin I, which in turn transforms to angiotensin II to function. Angiotensin II reduces blood vessels, increasing blood flow and causing high blood pressure or hypertension. On the contrary, the destruction of bradykinin reduces the ability of blood vessels to spread and reduce blood flow.

RAS is also known as the Renin-English system. This is because angiotensin II causesRelease of aldosterone, hormone that increases the amount of sodium and water entering the blood. This also increases blood pressure because such re -absorption increases the extracellular body volume.

In addition to hypertension, the effects of the enzyme converting angiotensin contribute to diseases such as heart failure and diabetes. There are specialized drugs called ACE inhibitors that inhibit the enzyme by reducing angiotensin II and bradykinin degradation. Among examples of ACE inhibitors are Benazepril, which is sold under the Lotensin brand; Capotril, which concerns the Capoten brand; and Lisinopril, which was branded or stalled.