What is fatty acid synthas?

fatty acids have an acid group at one end connected to a hydrocarbon chain that repels water. These are very important cellular components that serve structural roles as membrane components, signaling roles as hormones and as a source of energy for fuel metabolism. People get many types of fatty acids from their diet, but the body must be synthesized by several types. The synthesis of fatty acids is mediated in mammals with a large pair of proteins containing a number of different enzymes that cooperate and are known as synthas of fatty acids (FAS). The basic reaction of fatty acid synthesis is to combine molecules composed of two carbon units into longer chains to form fatty acids. Fatty acid consisting of mammals is a 16-carbon compound of palmitic acid, also known as C16. Palmitic acid is saturated fatty acid, which means that neontain of any double bond. Biosynthesis of this compound takes place in cytosol and there is no connection with membranes.

Palmitic acid synthesis requires more than two carbon fatty acid precursors and fatty acid synthas. It also requires a cupboard, which is a non -protein component freely associated with the enzyme. COA COFAFT is a sulfur -containing compound that accompanies each of the chemicals that serves as a source of carbon for a chain of fatty acids. The source of both carbon units, which are to be added to the growing fatty acid chain, is the three-legged Malonyl-Coa cavalry, which is produced from two-hiding acetyl-Coa compounds.

Fatty acid synthase must first be activated by contact with acetyl-CoA. After this FAS reaction, it gradually extends the nascent chain of fatty acids using carbon groups donated from Malonyl-Coa. This process requires a number of chemical reaction differences. As the chain grows, it passes from one enzyme to another until it reaches its final length of 16 carbons. Then they are releasedit from the protein.

There are two types of fatty acid synthas. FAS type I is a type of mammal that produces only palmitic acid using a large pair of proteins, each containing several different enzymes. In contrast, type II FAS is used by bacteria and plants. This multi-space complex has individual enzymes as separate proteins that clump together. The type II complex can create other types of fatty acids, but is not as effective as the mammalty type and the FAS.