What is the nigrostriatal way?

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nigrostriatal path is defined as a connection between two areas of the brain called nigra amd Substantia. The adjective nigrostriatal is a combination of Latin words niger for the black color of the nigra and stria for the striped Striata Institute. They are four main dopamine or dopaminergic brain pathways, one of which is the nigrostriatal way. This path is also considered to be part of a loop of basal ganglia, which is a functional unit associated mainly with cognitive control.

consisting of prolonged neurons, which are covered with myelin for electrical insulation, usually referred to as white matter, nigrostriatal path is generally classified as a nervous path. In addition, it is subcategory as a dopamine path. This is because it is one of the connections that carry dopamine, substance or neurotransmitter instrumental when facilitating movement. It is therefore similar to other lanes such as mesocortical path, mesolimbic track and tuberoinFundibular track.

The substantial substance that is Latin for the "black substance" is part of the brain that contains dopamine. The Nigrostriatal Rail transports the neurotransmitter from the essential nigra, which is located in the mestencephalon or midbrain, to the striatum at the bottom of the ponos or front brains. The striatum is also known as a non -nostriatum or strip core, it is the primary entrance port of basal ganglia, using dopamine helping to control movement.

Because dopamine is important in motion, some health conditions have been associated with cases where there is a shortage involving the nigrostriatal path. The occurrence of Parkinson's disease, a degenerative disorder that affects the central nervous system (CNS), is associated with the neurons of the death of Carrying Dopamin, which is located in the nigra substantia. Since 2011, the cause of cell death has been determined. Pathological symptoms also do not become evident until nigrostriatnThe journey will not lose at least 80 percent of their dopamine skills.

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nigrostriatal path is also clinically important for induction of tardive dyskinesia. The type of disorder that includes an increase in involuntary movements is called "tardive" because symptoms tend to develop slowly - long after the onset of the disease. Tardive dyskinesis is associated with side effects of anti-psychotics that are used to treat mental disorders such as schizophrenia and manic depression. This is because such medicines are blocking dopamine receptors, that roads like nigrostriatal paths carry.