What is the relationship between Renin and Aldosterone?
The relationship between Renin and Aldosterone occurs in the physiological path that regulates blood pressure. Enzyme renin, relaxed by the kidneys, activates angiotensin production, protein messenger. This chemical signals the adrenal secretion of aldosterone, a hormone that reduces the amount of sodium and water secreted by the kidneys, increases blood volume and pressure. This path is an important factor in conditions such as high blood pressure and is monitored in cases of cardiovascular disease.
Renin and aldosterone are part of the physiological feedback mechanism that regulates the volume of blood and cardiac output by control of vascular resistance, especially arterial blood pressure. They are components of the Renin-English system of the system. Renin is an enzyme circulated by the juxtaglomerular kidney apparatus, released in response to signals from the sympathetic nervous system, or when blood volume is low enough. Increased ahormy renin in the bloodstream triggers the production of angiotensin, chemical messenger, ktErý increases blood pressure by reducing arteries and veins.
After the activation of angiotensin, the adrenal glands induce to secrete Aldosterone, steroid hormones. When the messenger circulates in the bloodstream, they cause sodium and water to reabsorb in the kidneys rather than exclude. Potassium is also deleted, which increases the total blood volume. This mechanism increases the primary effect of renin and aldosterone - elevated blood pressure -. The sympathetic nervous system sometimes also increases heart rate by releasing Epinephrine simultaneously, which strengthens the effect of the RAA system.
regulation of renal minerals with substances such as renin and aldosterone is a particularly important step in controlling blood pressure. The sympathetic nervous system and cells in the kidneys themselves affect the path. Neurological feedback slows down the renal excretion of sodium and water, while local sensors in the juxtaglomerular apparatus react by loosening more renin. LipThe ence of sodium in the body is not only in the kidneys. Aldosterone prevents the loss of sodium in sweat also by induction of potassium ions.
Renin and aldosterone laboratory tests are used to determine whether sufficient or excessive hormone levels are formed and help indicate the causes of non -functional blood pressure regulation. Increased diet sodiums, obesity and many other factors can cause RAA to work too much, as well as disorders that cause adrenal glands to secrete too much aldosterone. This results in high blood pressure, also known as hypertension. Some drugs used to treat this condition block aldosterone receptors, reducing arterial pressure and reducing the effects of feedback.