What Are Indoleamines?
Serum 0.22-2.06 mol / L (39-361ng / ml).
Serotonin test
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- 5-HT, also called serotonin, is derived from tryptophan. Tryptophan is formed by tryptophan hydroxylase to form 5-hydroxytryptophan, and then decarboxylase to 5-HT. 5-HT is a central nervous system delivery substance, the active part of which is indoleamine. It is widely present in the brain, platelets, stomach and other tissues, with the largest content in the brain, and is a strong smooth muscle stimulator and vasoconstrictor. It is high in platelets and participates in vasoconstriction after platelet rupture and release. Two-thirds of 5-HT is excreted after the liver is combined with sulfuric acid or glucuronic acid, or indole is cleaved and broken down; about one-third is oxidized and deaminated by monoammonoxidase to form 5-HLAA and excreted from urine. 5-HIAA is the final product of 5-hydroxytryptophan metabolism and has no biological activity.
- Name
- Serotonin test
- category
- blood
- Serum 0.22-2.06 mol / L (39-361ng / ml).
- (1) Elevation: Carcinoid tumor syndrome, postoperative dumping syndrome, migraine, hypoxia, etc. (2) Reduced: Systemic lupus erythematosus (SLE), rheumatoid arthritis (rheumatoid arthritis), connective tissue diseases such as mixed connective tissue disease, Parkinson's disease (tremor paralysis), chorea, liver disease Nuclear degeneration (Wilson's disease), schizophrenia, neurasthenia, etc.
- It can also rise after eating a lot of walnuts and bananas.
- Small bowel tumors, Alzheimer's disease