What is combinatorial synthesis?
combinatorial synthesis is a technique used by chemists to create a large number of related or similar chemical compounds to compare them. By compiling data about a group of compounds called a combination library, the chemist can use this data to select specific compounds for further research. Much of this type of work is done virtually by sophisticated software, allowing chemists to quickly collect information about all possible compounds that can be created using the required base or set of components or molecules. You can then select and synthesize promising compounds for testing in the laboratory.
Advances in computer technology have very advanced techniques of combinatorial synthesis and allow chemists to quickly create combinatorial libraries with a very large number of similar but different compounds. Some databases of this type may contain millions of different compounds. The idea of combinatorial synthesis WJAK first developed in the second half of 20. century, but in the 1890s. The 20th century became a widely used tool with rapid development of computing power available to scientists.
Pharmaceutical companies are one of the main users of this technique that allows you to discover and select potentially useful medicines for the earliest phases of testing much faster than previously possible. By using sophisticated software, scientists are able to practically synthesize whole compound families in seconds that would otherwise take years if they were made in the laboratory. This software can also help them choose certain compounds for further testing and for real conditions. In this way, many new drugs can be developed and introduced for use much faster than otherwise possible.other chemistry fields can also use the principles of combinatorial synthesis. Scientists use this technique in many academic and industrial fields. The process can be usedFor the development of new polymers, oil products and insecticides. Scientists at the University of Berkeley in California used combinatorial synthesis to develop a whole family of metal compounds called magnetoreactive compounds. These compounds have a character of different conductivity when they are subjected to certain magnetic fields.
This technique is still relatively new and will undoubtedly provide great support for research in a number of areas in the 21st century. Almost any field that relies on chemistry in any way for the development of new compounds can benefit from combinatoric synthesis. A chemist or researcher can use software to help find compounds with the required characteristics or properties in a fraction of the time required to carry out the same research by other methods.