What are the causes of neutropenia?

neutropenia is a condition in which one does not have a high amount of neutrophils in the blood. Neutrophils are a type of white blood cells that are primarily responsible for protecting the body from bacteria, mushrooms and other alien substances. People who have neutropenia are a much higher risk of developing infections and diseases. The causes of neutropenia tend to be other basic health problems that may end in the destruction of neutrophils. Bone marrow is a substance found in bones that helps produce blood cells. Some conditions may prevent bone marrows to fully produce blood cells. These conditions include myelocathexis, a condition that causes a reduction in the amount of white blood cells and Kostmann's syndrome in which one is born almost without neutrophils in his blood. The conditions affecting bone marrow tend to be present at birth and are considered to be the result of genetic abnormalities. Some types of cancer such as lymphoma and leukemia may cause abnormal cancer cells to accumulate in the bone marrowAnd it will prevent effective neutrophil production. Chemotherapy and radiation, two of the most common treatments used to destroy cancer cells, can also damage the functioning of bone marrow as a side effect and may result in neutropeny.

Some drugs may disrupt the production of bone marrow neutrophils. Antibiotic drugs commonly used to treat bacteria infections may negatively affect the functioning of bone marrow. It has also been found that diuretics is one of the potential causes of neutropenia. Diuretics, often referred to as water pills, are a category of drugs that cause a person to urinate a mud than usually to remove excess water and salt from the body and can be used to treat conditions such as high blood pressure, kidney disease, heart failure and liver disease. Other medicines that may cause neutropenia as a side effect include penicillin, some NestEroidal anti -inflammatory drugs and inhibitors of enzyme converting angiotensin (ACE).

Autoimmune disorders, conditions under which the body begins to attack its own substances, as if they were harmful antibodies such as bacteria, viruses or fungi, can also be one of the causes of neutropenia. Rheumatoid arthritis, a disease that causes severe stiffness and pain primarily in joints, is one of the most common autoimmune disorders that can contribute to neutropenia. Other autoimmune disorders that may be associated with neutropenia include lupus and Felty syndrome.