What is the bone marrow match?
The bone marrow load occurs when the bone marrow donor has pulp that corresponds to someone who needs bone marrow transplantation. People who are diagnosed with a serious immune system, blood or genetic diseases may decide to undergo bone marrow transplantation as one of their therapeutic options. Bone marrow transplantation replaces unhealthy cells that form blood with healthy cells from the donor. Once a person decides to continue with transplantation, he must find a donor with a successful bone marrow match. HLA means antigen of human leukocytes, a hereditary protein found on most cells in the body. These proteins function as markers and mean which cells belong to the body and which are not. Because these markers are hereditary, each person has two sets that include one of each parent.
To evaluate the bone marrow, doctors look at six HLA antigens, but many transplant centers look at eight or ten antigens. For a successful bone marrow agreement must be withfeast at least five antigens. The process used to ensure the best possible match for donors and recipients is called confirmation writing. Bone marrow transplantation used by other persons is called allogeneic bone marrow transplants and are the most popular.
Because the HLA tissues are genetic, most doctors first look for a donor in the family, with the best chance to adapt siblings. It is important to realize that not all people with siblings will have a successful match. According to the National Donor Program, only 30 percent of bone marrow recipients will find a successful match in their family. If a match in the family cannot be found, doctors control the national bone marrow register. Finding a successful bone marrow match on registers is purely lucky. Sometimes there is an immediate match and sometimes the recipient has to wait weeks or months before finding the match.
is a common misconception that the donation of bone marrowIt is a painful procedure. The blood marrow donor, which was associated with the recipient, must undergo surgery. Donors are served by anesthesia and hollow needles are used to draw liquid marrow from the back of the pan. There will be mild pain at the bottom of the back for several days. Most donors return to normal daily activities within a few days and can expect their bone marrow to be completely regenerated within four to six weeks.