What Is Alizarin?

Alizarin is a typical mordant dye. Can be extracted from the root of Rubia cordifolia. Alizarin was used as a red dye in Central Asia, Egypt, Europe and China as early as 3500 years ago. In 1826, Pierre Jean of France confirmed that Madder Root contained two dyes, Alizarin Red and Purpurin. This textile, which has been used as a natural plant dye in the past to make hot red, can be used to make new "green" batteries through the latest technology.

Scientific name: 1,2-dihydroxy-9,10-anthraquinone qiàn molecular weight = 240.23

Alizarin is a typical medium

CAS number: 72-48-0

MDL number: MFCD00001201

EINECS number: 200-782-5

RTECS number: CB6580000

BRN number: 1914037 ^[1]

Properties: orange-red crystal or ocher yellow powder

Density (g / mL, 20/4 ): 1.06

Melting point (ºC): 289.5

Boiling point (ºC, normal pressure): 430SU

Flash point (ºC): 430 (subl.)

Solubility: Easily soluble in hot methanol and 25 ° C ether. Soluble in benzene, glacial acetic acid, pyridine, carbon disulfide, slightly soluble in water

Red needle-like crystals. The melting point is 289 ~ 290 ° C, the boiling point is 430 * C, and the molar heat of combustion under equal pressure is 6062J / moL. Easy to sublimate, almost insoluble in water, 100g of water can dissolve 0.034g at 100 * C. Soluble in ethanol and

Acute toxicity: Wild bird oral LD50: 316 mg / kg;

Mutagenesis: Salmonella Mutation in microorganismsTEST SYSTEM: 100 ug / plate;

B. subtilis DNA repairTEST SYSTEM: 2 mg / disc;

Rat liver Unscheduled DNA synthesisTEST SYSTEM: 10 mg / L;

Salmonella Mutation in microorganismsTEST SYSTEM: 100ug / plate; ^[1]

1. Molar refractive index: 62.43

2. Molar volume: 155.9

3. Isotonic specific volume (90.2K): 465.2

4. Surface tension (dyne / cm): 79.2

5. Polarization rate: 24.74 ^[2]

1. Hydrophobic parameter calculation reference value (XlogP): None

2.Number of hydrogen-bonded donors: 2

3.Number of hydrogen bond acceptors: 4

4.Number of rotatable chemical bonds: 0

5.Number of tautomers: 16

6. Topological molecular polar surface area

7.Number of heavy atoms: 18

8.Surface charge: 0

9.Complexity: 378

10.Number of isotope atoms: 0

11. Determine the number of atomic stereocenters: 0

12. Uncertain number of atomic stereocenters: 0

13. Determine the number of chemical bond stereocenters: 0

14. Uncertain number of chemical bond stereocenters: 0

15. Number of covalent bond units: 1 ^[2]

1. Stable under normal temperature and pressure.

2. It is irritating. Avoid dust inhalation and contact with eyes and skin during use. ^[2]

Keep sealed. ^[2]

Alizarin exists in the roots of Rubiaceae in nature. Anthraquinone-2-sulfonic acid is co-melted with caustic soda and potassium chlorate or potassium nitrate, then the molten substance is poured into hot water, and then alizarin is precipitated with hydrochloric acid: 9 g of potassium chlorate, 30 g of anthraquinone-2-sulfonic Sodium and 110g of sodium hydroxide were dissolved in 110ml of water at the same time, and 25g was heated and reacted at 170 ° C in an autoclave. After cooling, the reaction was extracted with water several times, 150 ml each time. The water extract was filtered and the filtrate was acidified with hydrochloric acid. After cooling, the precipitate precipitated was suction-filtered, washed, and dried to obtain about 20 g of alizarin. ^[2]

1. Acid-base indicator. It is used as drip reagent for aluminum, indium, mercury, zinc and zirconium. Nervous tissue and protozoa live stain.

2. Rubiamin has an inhibitory effect on the growth of Staphylococcus aureus, and can inhibit the permeability of connective tissue in the skin of rats. Similar to rutin, it may have an anti-inflammatory effect. It is safe to use as a cosmetic pigment and lipstick pigment without any side effects. Combined with some phenolic hydroxyl and aniline derivatives, it can be used as a non-irritating oxidative hair dye auxiliary, making the color soft and long-lasting. ^[2]

Acid-base indicator (0.5% solution), pH discoloration range 5.5 (yellow) to 6.8 (red); used as a drip reagent for aluminum, indium, mercury, zinc and zirconium; a staining agent for nerve tissue and protozoa living stain

Dyes, can be used for dyeing and printing of cotton, and is synthetic similar to its structure

I. Emergency Response to Leakage

Cut off the fire. Wear self-contained breathing apparatus and general fire protective clothing. Stop leaks while ensuring safety. Water spray reduces evaporation. Absorb with sand or other non-combustible adsorbent. It is then transported to an open area for burial, evaporation, or incineration. If there is a large amount of leakage, use a dike to contain it, and then collect, transfer, recycle or harmlessly dispose of it.

Second, protective measures

Respiratory protection: When the concentration in the air is high, you should wear a gas mask. It is recommended to wear a self-contained breathing apparatus for emergency or rescue.

Eye protection: Wear chemical safety protective glasses.

Body protection: Wear antistatic work clothes.

Hand protection: Wear protective gloves.

Others: Smoking is strictly prohibited on the job site. Avoid prolonged repeated exposure.

Third, first aid measures

Skin contact: Remove contaminated clothing and rinse thoroughly with soap and water.

Eye contact: Open the upper and lower eyelids immediately and rinse with running water for 15 minutes. Seek medical attention.

Inhalation: Remove from the scene to fresh air. Difficulty breathing to give oxygen. Once breathing stops, begin CPR immediately. Seek medical attention.

Ingestion: If you take it by mistake, rinse your mouth with water, drink plenty of warm water, induce vomiting, and consult a doctor immediately. ^[3]

Safety identification: S22S24 / 25

Danger Code: Xi

Danger level: R36 / 38-36 / 37/38

Security level: S26-36-24 / 25-22 ^[2]