What Is an IgM Antibody?
IgM antibodies are generally protective antibodies and are immune.
IgM antibody
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- Chinese name
- IgM antibody
- Mainly exist
- Living body blood
- main effect
- To prevent bacteremia
- Features
- Immune
- IgM antibodies are generally protective antibodies and are immune.
- IgM is mainly present in the blood of organisms and plays a major role in preventing bacteremia. Therefore, the determination of IgM antibodies has higher clinical diagnostic value for certain infectious diseases such as hepatitis A.
- IgM antibody is the first secreted antibody in the immune response. Once the infection is rapidly generated, the amount of IgM antibody gradually decreases and disappears after a period of time. They initiate complement cascades after binding to the antigen. They also connected the invaders to each other and gathered into a pile to facilitate the engulfment of macrophages. IgM in the mother cannot pass through the placenta. If IgM is found in the blood of the fetus or newborn, it means that an intrauterine infection has occurred.
- IgM accounts for 5% to 10% of the total serum immunoglobulin, and the serum concentration is about 1mg / ml. The monomer IgM is expressed on the surface of B cells in a membrane-bound manner and constitutes a B cell antigen receptor. Igm is the earliest antibody to appear in the primary humoral immune response, and is the leading force in the body's anti-infection. The detection of IgM in the serum indicates that a new infection has occurred and can be used for early diagnosis of infection.