What is fusariosis?

Fusariosis is an infection caused by the type of fungus fusarium . Infections of these mold species are most often observed in people who are immunocompromised, which means that their immune system has been somehow weakened. Fusariosis is treatable, but requires the infection to be diagnosed rapidly. In addition, successful treatment requires the patient's immune system to be strengthened in some way to prevent reinfection.

While other mold species have been responsible for opportunistic infections in immunocompromised people, the Fusarium molds are becoming increasingly common. Hlavním důvodem tohoto posunu je to, že nové a účinnější typy chemoterapeutických léčebných postupů vedou k většímu stupni potlačení imunitního systému u mnoha pacientů, přičemž tyto lidi zůstávají zranitelnější vůči infekci. People with hematological malignancy such as leukemia, and people who have undergone bone marrow transplants tend to be subject to highly immunosuppressive chemotherapy. Fusariosis may be fatal in these cases. This is because the form releases more disputes in such climate. The most common methods of infection are breathing in spores or infections through breaks in the skin.

Fusariosis people usually have symptoms such as high fever, which does not respond to treatment with antimicrobial drugs, pulmonary infections and skin lesions. The lesions are fine to the touch and are usually found at the ends of the body. One or more organs may also be affected. Accurate diagnosis often requires that tissue biopsy distinguishes between fusarius and other mold species.

Fusariosis is particularly dangerous because the type fusarium fungi infect people, they are able to produce fungal toxins known as mycotoxins. Toxins produced by these species are able to further suppress the immune system, helping the infection spread. With a further suppressed immune system is an infectioneven more difficult to treat effectively.

Another factor that increases the difficulty of treatment is that these infections are often resistant to antifungal drugs. Currently, the main drugs are used to treat such infections of ampotericin-B and a broad-spectrum antifungal called voriconazole. Due to the problems of drug resistance and toxin production in the form, this treatment is usually combined with other drugs that help to stimulate the growth and activation of new immune cells. In some cases, infected tissue must be surgically removed to prevent reinfection.