What Is Fusariosis?

Fusarium is also called skin, cornea or systemic infection caused by Fusarium. Fusarium is a saprophytic that is associated with soft tissue infections, keratitis, and onychomycosis in immunocompetent hosts. Due to the application of cytotoxic drugs in the treatment of leukemia and the increase in organ transplants, the number of invasive and disseminated Fusarium infections has increased year by year in the past 20 years. Fusarium can cause infections through the skin, mucous membranes, and respiratory tract. Sporadic Fusarium occurs almost exclusively in immunocompromised patients.

Basic Information

English name

fusaridiosis; fusariomycosis

Visiting department

dermatology

Common locations

Skin, cornea

Common causes

Fusarium bead, Fusarium solani, Fusarium oxysporum, etc.

Common symptoms

Mainly chronic granuloma, with early manifestations of erythema, pimples, nodules, and subsequent damage can be fused into granulomas, and sometimes granulomas can rupture

Causes of Fusarium

Fusarium is a conditional pathogen. It is easy to cause skin damage and decreased human immunity. The common pathogens are F. moniliforme, F. solani, and F. oxysporum. ), Etc., Fusarium is one of the most common pathogens that cause keratitis and corneal ulcers. It can also cause endophthalmitis, osteomyelitis, arthritis, sinus infections, onychomycosis, and foot fungi. Fusarium on burned skin It can multiply on tadpoles and tissue debris, but generally does not invade surrounding tissues, which can cause disseminated infections.

Clinical manifestations of Fusarium

The main manifestations are chronic granulomas, with early manifestations of erythema, pimples, and nodules. Later damage can be fused into granulomas, and sometimes granulomas can rupture, without obvious scars after healing. Skin lesions may have itching.

Fusarium diagnosis

According to clinical manifestations, take dandruff, pus, nail scraps, corneal ulcer scrape, living tissue, etc., under the microscope, branches, separated hyphae can be seen under the microscope, similar to Aspergillus microscopic characteristics, on sandcastle medium, gas The mycelium is abundant, and the micro and large conidia can be seen under the microscope, and the diagnosis is not difficult.

Fusarium Treatment

Ketoconazole or itraconazole can be used for at least one year, and the dose is large. The therapeutic dose depends on the susceptibility of the pathogen to the drug.