What is macular amyloidosis?

macular amyloidosis is a skin or skin condition that is characterized by flat -colored spots of the skin called macula. It falls into the category of disorders called amyloidosis, which includes the storage of amyloid proteins in organs or tissues in the body. This type of accumulation usually causes damage to affected areas by preventing normal function. Brown or gray are the usual pigmentation manifestations, with the usual place of occurrence is the upper back. In some cases the eruptions appear on the arms.

Macular amyloidosis is one of three conditions in the category of primary skin amyloidosis and the most common. The other two are amyloidosis lichens, which is characterized by prritical lichenoid skin increases; and nodular amyloidosis, named for its small rounded lumps. Each condition is associated with a receptor protein known as oncostatin-M specific receptor subunit beta or onkostatin-M receptor. Some medical scientists believe that mutations of this substance may lead to the appearance of suchthe diseases.

Although the exact cause of macular amyloidosis is still unknown, the medical community has designed two main possibilities. The first hypothesis is called the theory of fibrillary body, which indicates that two groups of cells - fibroblasts that act as connective tissue cells; and macrophages, white blood cells that eat substances that pose a risk of infection - turn prematurely dead cells in an epidermis or outer layer of skin to amyloids. Another explanation, secretory theories, suggests that they are the basic cells found in the innermost epidermal layer that form the amyloid when they fall apart.

macular amyloidosis is a condition that affects adults. Studies have shown that the disease is predominant in women than men. It also tends to be more common among South Americans, Asians and the Middle East.

There are different types of treatment methods for macular amyloidosis. Antihistaminics or antagonists of histamine, such as chlorfeniramin and diffenhydramine, are used to inhibit organic compounds of histamine, reducing allergies; And agents such as dimethylsulfoxide are applied to reduce inflammation. Other treatment methods include the application of ultraviolet B (UV-B) and surgical excision of macul. However, a completely effective or successful remedy for macular amyloidosis must still be invented or discovered and the disease remains to be eraded for a long and extremely.