What is Neuropsychiatric Lupus?
Central lupus erythematosus (NSLE) is a brain complication of systemic lupus erythematosus, which is manifested as headache, epilepsy, aseptic meningitis, cranial neuropathy, and mental symptoms. It is easily misdiagnosed as other centers when it is the first symptom. Nervous system disease.
Central lupus erythematosus
- Chinese name
- Central lupus erythematosus
- Part of speech
- noun
- Concept
- Brain complications of systemic lupus erythematosus
- which performed
- Headache, epilepsy, aseptic meningitis, etc.
- Central lupus erythematosus (NSLE) is a brain complication of systemic lupus erythematosus, which is manifested as headache, epilepsy, aseptic meningitis, cranial neuropathy, and mental symptoms. It is easily misdiagnosed as other centers when it is the first symptom. Nervous system disease.
- The patient had no serious damage to other systems, no severe central nervous system manifestations such as major epilepsy, cerebral infarction, and cerebral hemorrhage. He was then given an intravenous infusion of methylprednisolone 80mg without an impact dose, and no intrathecal injection was added. The treatment effect was satisfactory. . In this case, do you still need to choose conventional high-dose methylprednisolone impact plus cyclophosphamide impact treatment? Its long-term efficacy and complications were not significantly different from those of high-dose methylprednisolone shock + cyclophosphamide shock.
- The diagnosis of NPLE also needs to be distinguished from neuropsychiatric symptoms secondary to SLE. The fever and central nervous system manifestations of newly diagnosed SLE are mostly due to disease activity. Treated SLE should not ignore infection and adverse drug reactions. Due to the use of hormones and other immunosuppressants, the body's resistance is low. SLE patients are prone to bacterial, fungal, viral, and parasitic infections. Routine, biochemical, and etiological examination of the cerebrospinal fluid can help rule out central nervous system infection. Various drugs used in the treatment of SLE, such as glucocorticoids, antimalarials, non-steroidal anti-inflammatory drugs, cytotoxic drugs, etc., can cause central nervous system toxic effects, such as central nervous system symptoms during drug treatment, Be careful to distinguish.