What is an oral submucosal fibrosis?

oral submucosal fibrosis (OSF) is a health condition that affects the mouth by causing inflammation of mucosal tissues and the formation of fibrous growth on the walls of the mouth. It causes progressive immobilization of the jaw during the disease, resulting in the overall paralysis of the jaw over time. This situation is described in 1952 by J. Schwartz, who studied a group of Asian-Indian women living in Kenya. This disease is also associated with the consumption of spicy foods such as red chils, dietary shortcomings, extreme climate and immunological conditions.

When oral submucosal fibrosis is detected in the early stages, it stops consuming an irritant, such as the ARECA matrix used in betel quizzes or chewing tobacco, often solved. However, most patients seek medical attention when the disease becomes mild to severe. At this stage, the symptoms of oral submucose fibrosis are not reverbible and treatment is symptomatic and focuses on restoring a certain degree of oral movement in response to paralysisjaws. Treatment by injection of bone marrow stem cells was effective in improving the extent of movement in the mouth.

Further treatment of oral submucosal fibrosis includes the course of hydrocortisone injected into the mucosa daily for two to three weeks, depending on the severity of the disease. Chewing hydrocortisone pellets are also prescribed and chewed every three to four hours for three to four weeks. Injection of human chorionic gonadtrophin (HCG) in two to three doses per week for three to four weeks were also effective in the treatment of oral submucosal fibrosis. Surgery is indicated when the space between the patient's teeth has been reduced to 2 cm or less.

In conjunction with the above -mentioned treatments, there are several other considerations that the patient may take to potentially improve or delay the symptoms of oral submucosal fibrosis. Pentoxifyllin, a medicine that works on a loss of visczIts blood blood blood is sometimes prescribed to improve blood supply to the affected tissues. Patients also usually advise to avoid hot drinks such as coffee and tea, as well as potentially irritating fluids such as alcoholic beverages. The doctor also usually recommends that the patient avoids the consumption of spicy foods and other substances that tend to irritate the mucous membranes in the mouth.