What Is Parinaud Syndrome?

Parinaud syndrome, Parino syndrome, also known as the upper thalamic syndrome, the midbrain and tectum syndrome, the supine upward paralysis syndrome.

Parinaud syndrome

Overview of Parinaud syndrome

Parinaud syndrome, Parino syndrome, also known as the upper thalamic syndrome, the midbrain and tectum syndrome, the supine upward paralysis syndrome.

Eyeballs with vertical coronal movement in the lower cortex of the midbrain and vertical cortical movement caused by vertical synapse of the lower cortex, involving the destructive lesions of the superior colliculus can cause the two eyes to move in the same direction.

Causes and mechanisms of Parinaud syndrome

Intracranial tumors, such as pineal tumors, corpus callosum tumors, midbrain tumors, and vascular lesions cause damage to the cortex of the cortex. The pathogenesis and mechanism are not clear.

Clinical manifestations of Parinaud syndrome

It is characterized by two eyes unable to look up at the same time, dilated or unequal pupils on both sides, photoresponse disappeared , and adjustment reflection exists.

Appears as dizziness and sometimes ataxia. Eyelid drooping, diplopia, paralysis of both eyes with upward vision, but no convergent paralysis. Withdrawal nystagmus, dislocation of pupils, and edema of optic nerve papillae at the fundus.

Differential diagnosis of Parinaud syndrome

(A) intracranial tumor

1. pineal body tumor: see Nothnagel's syndrome.

2. Carcass tumor (corqus callusum tumor): Here tumors invade adjacent brain tissue, clinical manifestations are actually the result of damage to adjacent structures. Tumors in the back of the corpus callosum can cause symptoms similar to pineal tumors. Early symptoms of Parinaud's syndrome appear, and hydrocephalus and intracranial hypertension are more likely to appear. Those with clinical manifestations of progressive dementia, accompanied by bilateral cerebral hemisphere damage and intracranial elevation should be considered.

(2) Cerebral infarction Parinaud syndrome may occur in infarctions in the midbrain and other parts, but it is often accompanied by focal symptoms such as other sensorimotor disorders. It starts more than when it is quiet and progresses for hours to days. , Sober-minded. Cerebrospinal fluid is clear and pressure is normal.