What is Rosai-Dorfman?
Rosai-Dorfman disease is a rare disorder marked by the accumulation of white blood cells called histiocytes that are excessively produced in the body. These white blood cells usually accumulate in human lymph nodes, especially in the throat. Accumulation can also affect other parts of the body less often. For example, this condition may affect the skin, kidneys and gastrointestinal system of the patient; In some cases, this may also affect the patient's central nervous system. No one knows what causes Rosai-Dorfman's disease, but sometimes it can be treated with chemotherapy, radiation or surgery.
When a person has Rosai-Dorfman's disease, histiocytes usually accumulate in the patient's lymph nodes. At the time of this accumulation of cells, it often causes enlargement of affected lymph nodes. In most cases, the extension is painless and the condition is benign. However, it can affect one part of the body or different parts of the patient's body at the same time. For example, this Disease can only affect the patient's neck or may also affectIvnit neck, eyes, kidneys of the patient and even the central nervous system.
also referred to as sinus histiocytosis with massive lymphadenopathy, this condition may not cause pain, but can cause many other symptoms. Symptoms that may develop when a person has Rosai-Dorfman's disease include enlargement of lymph nodes, liver and spleen. Patients with this condition can also develop fever and anemia and look pale. Some people with this condition can also experience an inexplicable weight loss, drain mucus from the nose or clogged nose. An individual may also develop pain and inflammation and inflammation of the joints in relation to the disease.
If the patient has a slight case of Rosai-Dorfman, he does not have to treat. In this case, the condition can spontaneously resolve the condition over time. It can last years. In serious cases, the physician may recommend chemotherapy, radiation therapy and sometimes surgeryKýký.
The prognosis for a person with Rosai-Dorfman's disease is generally very good. Less often this can cause a person's death or act as a contributing factor. In most cases, however, death results only from the disease of Rosai-Dorfman, when a person deals with a serious case that affects many organs of his body. Death may also be more likely for a person who has a basic problem of the immune system.