What Are Broad-Spectrum Antibiotics?
Broad-spectrum antibiotics refer to drugs with a broad antibacterial spectrum. In short, they are drugs that can resist most bacteria. There is also a narrow-spectrum antibiotic, which is a drug that specifically kills a certain type of bacteria.
- Drug Name
- Broad-spectrum antibiotics
- Foreign name
- wide-spectrum antibiotic
- Main indications
- When the pathogen is unknown but needs to be sterilized
- Drug type
- Drugs with a wide antibacterial spectrum
- Common classification
- Polypeptides, macrolides, etc.
- Harmful use
- Bacterial resistance, flora imbalance, side effects
- Broad-spectrum antibiotics refer to drugs with a broad antibacterial spectrum. In short, they are drugs that can resist most bacteria. There is also a narrow-spectrum antibiotic, which is a drug that specifically kills a certain type of bacteria.
- A broad range of antibiotics . For example, chloramphenicol, chlortetracycline, oxytetracycline, tetracycline, and sulfomycin.
Introduction to broad-spectrum antibiotics
- Broad-spectrum antibiotics
- Not only can it strongly inhibit most Gram-negative and Gram-positive bacteria, but it can also inhibit Rickettsia, Borrelia, and some protozoa. However, in use, because the normal balance of the microbiome in the body is broken, additional infections of insensitive microorganisms such as Candida may occur.
- Broad-spectrum antibiotics are mainly used for pathogenic bacteria, but when sterilization is needed, when specific pathogens are identified, narrow-spectrum antibiotics should be used for specific sterilization. Excessive use of antibiotics is not good for the body. It should be used under the guidance of a doctor and should not be taken by yourself.
Common classification of broad-spectrum antibiotics
Broad-spectrum antibiotic peptides
- The main antibiotics belonging to this class of antibiotics are bacitracin zinc, colistin, virginiamycin, thiopeptomycin, persistent mycin, enalamycin, and avomycin.
Broad-spectrum antibiotics macrolides
- Antibiotics are mainly absorbed from the intestinal tract and can produce cross-resistance, including tylosin, norbemycin, erythromycin, and spiramycin.
8 Broad-spectrum antibiotics 8 phosphorus-containing polysaccharides
- Commonly used are flavomycin and macromycin.
Broad-spectrum antibiotic polyethers
- Commonly used are monensin, salinomycin, lasalimycin, and Maduramycin.
Broad-spectrum antibiotic aminoglycosides
- One is antibacterial antibiotics such as neomycin, morphomycin, and apramycin; the other is nematode anthelmintic antibiotics, such as vipermycin A and hygromycin B.
Broad-spectrum antibiotic chemical synthesis
- Such antibiotics include sulfonamides, quinethanol, furazolidone, and nitrofurenol.
Broad-spectrum antibiotic hazards
- Antibiotic hazards
Broad-spectrum antibiotics , resistance
- In recent years, due to the large-scale application of broad-spectrum antibiotics, a large number of drug-resistant strains and mutant strains have appeared, resulting in the use of antibiotics more and more advanced, the use of more and more, increasing the burden on patients.
Broad-spectrum antibiotics , side effects
- Due to the long-term and large-scale application of antibiotics, side effects also increase. Such as high-dose intravenous penicillin can cause muscle spasms, and even the appearance of penicillin encephalopathy such as convulsions and confusing mistakes; streptomycin can be used in large quantities to see dizziness, headache, tinnitus, nausea, and even cause renal insufficiency.
Broad-spectrum antibiotics , flora imbalances
- Under normal circumstances, the human intestine has a normal flora of bacteria. When long-term application of broad-spectrum antibiotics in large doses, the normal flora is inhibited or killed, and the drug-resistant strains not only survive, but because they have lost the restriction of the normal flora against it, they have taken the opportunity to reproduce in large numbers, and pseudomembranous enteritis has appeared. Symptoms of severe flora.
Use of broad-spectrum antibiotics
- 1. When using antibiotics, it is best to choose sensitive antibiotics based on drug sensitivity tests;
- 2. Don't increase the dose at will;
- 3. After the infection is completely controlled, the drug should be stopped in time;
- 4. When the body resistance is low, use broad-spectrum antibiotics with caution. Once a bacterial flora disorder occurs, the original antibiotics should be stopped first, and then the sensitive antibiotics should be used to control the infection according to the type of pathogens.