What are the medical use of methylene blue?
methylene blue, commonly used stain used to strengthen tissue samples monitored under the microscope, also has wide medical applications. In addition to dying tissue during diagnostic and surgery, this substance also works as an antidote for cyanide poisoning. It is used for the treatment of methemoglobinaemia, a condition characterized by the inability of blood to effectively bear oxygen. As a medicine, methylene blue can be used orally or intravenously. His potential role in the treatment of malaria, Alzheimer's disease and cancer is a continued area of research.
Potassile and carbon monoxide poisoning was treated with methylene blue as an antidote. During the 30th years it was first used for cyanide poisoning and was employed during the mid -20th century to treat carbon monoxide exposure. Hyperbaric oxygen, which is still used to poison cyanide, has replaced it as a preferred method of treatment of carbon monoxide exposure. Another historical use of the Drug is for the treatment of malaria; For this purpose is restoredInterest due to its cost efficiency.
methemoglobinaemia is an excess of methemoglobin in the blood. Unlike hemoglobin, methemoglobin cannot carry vital oxygen into cells and tissues of the body, causing characteristic pale or bluish skin associated with this disorder. This condition may be congenital or caused by exposure to certain chemicals. Infants are particularly susceptible to the methemoglobinaemia acquired when they are exposed to excessive nitrate levels in water caused by agricultural drainage. Methylene blue is generally administered intravenously to the treatment of acquired methemoglobinaemia, while oral doses are administered for the innate type of disease.
Methylene blue also acts as an inhibitor of monoamine oxidase (Maoi) and is used in the treatment of depression and anxiety. Serious side effects Ca occurs when this drug is used with selective serotonin reuptake (SSRI). Used twhen in the production of antipsychotic drugs prescribed to treat schizophrenia and other disorders. Research continues to use with Alzheimer and Parkinson's diseases.
In conjunction with antibiotics, methylene blue is administered orally to treat urinary tract infections. The blue dye is also used in diagnostic and surgery of bladder and other tissues and organs. It helps medical procedures by tissue improvement, which makes it easier to view. Methylene blue is used during laparoscopic, endoscopic and X -ray procedures.
Studies continue to investigate roles that this medicine could play in the treatment of cancer. It is used to map the lymph nodes in breast cancer and is used effectively to treat neurotoxicity caused by chemotherapeutic iphosphamide. Methylene blue induces apopt cancer cells as a direct treatment of cancer. Its use in conjunction with light is also studied for the treatment of cancer and other diseases.
Urine arvement and patient feces are a common side effect of this drug. Both could turn into a blue color that stops after the drug. Other side effects include nausea, vomiting and diarrhea. Rare side effects include fainting, excessive fatigue and irregular heart rhythm.