What is adoptive immunotherapy?
Immunotherapy is an developing field of disease treatment. This treatment involves using the body's immune response to combat diseases such as cancer. Adoptive immunotherapy is one type of treatment and refers to the implantation of immune cells into an infected or cancerous organism.
cells used in adoptive immunotherapy include lymphocytes infiltrating tumor (til) that destroys tumor cells with strong enzymes and cells of the killer activated by lymphokin (lacquer). Cell varnishes require the presence of interleukin-2 (IL-2) compounds to attack tumors. For this reason, the IL-2 is administered with cells during treatment.
In this form of immunotherapy, immune cells are removed from the patient, often from the tumor site. Til cells from these places represent a stronger response to tumors than cells found elsewhere in the body. During this time, the patient also receives IL-2 intravenously.
Immune cells are grown outside the patient in the amédium containing IL-2. The cells are then introduced to the patienti. After this infusion, the body begins to produce more cell lacquer, because the reconstructed cells usually mount a strong immune response to tumors.
Studies have shown that the introduction of cytokines such as IL-2 is necessary for the success of adoptive immunotherapy. The combination of Il-2 and varnish in this therapy is usually more effective than using cell lacquer itself. The reason may be that some tumors are immunosuppressive and can discourage the immune response in the nearby nearby. IL-2 infusion in the patient can help stimulate immune cells such as cell lacquers to attack tumor cells.
Adoptive immunotherapy may also include a combination of immune cell infusion, such as lymphocytes, along with antibodies that specifically focus on tumors. Antibodies that focus on the protein present on the CEPRO breast cancer surface This method was used by LLS. Combined with immune cells of T-lymphocytes in someErky studies have helped these antibodies to create an answer that eliminated cancer cells that spread to other parts of the body.
various cancer states can be potentially treated with adoptive immunotherapy. Cancer treated in this way include melanoma and ovarian carcinoma. Ovarian cancers usually cause a strong immune response, so they are particularly excellent candidates for this type of immunotherapy. The immune response to these cancers may often predict the patient's prognosis after surgery and chemotherapy.
Other diseases and types of cancer could be potentially treated with adoptive immunotherapy. They include breast cancer and cancer -free diseases such as Alzheimer's disease. Experiments are performed to determine how effective immunotherapy is to combat these diseases.