What is Fidaxomicin?
doctors can prescribe fidaxomicin for treatment Clostridium difficile and related diarrhea. The oral anti -infectious product specifically focuses on Clostridium organism. Reports suggest that fidaxomicin causes less gastrointestinal side effects commonly associated with antibiotics. Studies also indicate that fewer patients undergoing treatment with treatment experience the revival of bacterial colonization.
Fidaxomicin belongs to the group of macrocyclic antibiotics. These specific pharmaceutical drugs have a molecular structure composed of a large macrolide ring to which one or more sugars are attached. Laboratories formulate fidaxomicin by fermenting bacteria known as dactylosporangium aurarantiacum.
The method of effect of the drug includes the inhibition of the enzyme required by ribonucleic acid (RNA). RNA performs intracellular functions that include protein formation and cell replication. Bacteria die from preventing normal cellular activity. Before prescribingMeshs usually make a stool culture that positively identifies specific types of bacteria. The use of Fidoxomicin for infections other than Clostridium difficile can produce resistant tribes of other bacteria species.
The minimum amount of drugs is actually absorbed by the intestine. Most remain in the intended place. Unlike many other antibiotics, Fidaxomicin does not exclude normal flora that can cause yeast infections. Patients generally take one tablet of 200milliger Fidoxomicin, with or without food, twice a day for 10 days.
Typical side effects associated with anti -infectious are abdominal pain with possible nausea and reversal. In rare cases, patients may have sufffer gastrointestinal bleeding. Some patients may experience anemia with a special decrease in the number of neutrophils, white blood cells that are part of the immune system that fights againstinfection.
as Clostridium difficile, or c. Diff, bacteria naturally exist in the environment, healthy people usually have bacteria in their digestive tract. Scientists report that c. Diff tribes have become more resistant and infections more frequent and more serious. Individuals with endangered immune systems, recent hospitalizations or recent antibiotic therapy are more likely to develop bacteria overpopulation.
bacteria produce toxins that irritate the lining of the intestine, and inflammation creates symptoms that usually begin abdominal discomfort and watery diarrhea. Among serious or life -threatening symptoms that require medical intervention. The infection can quickly lead to dehydration, electrolyte imbalance and weight loss.