What Is the Glomerular Filtration Rate?
The amount of ultrafiltrate generated by the kidneys on both sides in a unit time (per minute) is called the glomerular filtration rate. It is one of the important indicators to measure renal function.
- Chinese name
- Glomerular filtration rate
- Reference
- 125m 15min / min for men, 10% lower for women
Basic Information
Clinical significance of glomerular filtration rate
- 1. Increased glomerular filtration rate can be seen in
- (1) In the early stage of diabetic glomerulosclerosis, due to increased secretion of growth hormone, glomerular hypertrophy is promoted, and glomerular filtration rate is increased.
- (2) In some micropathic nephrotic syndromes, the glomerular capillary colloid osmotic pressure is reduced, and the glomerular lesions are light, so the filtration is increased.
- (3) The glomerular filtration rate during pregnancy can increase, and it returns to normal after delivery.
- 2. Reduced glomerular filtration rate can be seen in
- (1) Various primary and secondary kidney diseases that affect glomerular filtration function.
- (2) With the aging, the glomerular filtration rate is gradually reduced. After 40 years of age, the glomerular filtration rate is reduced by 1.15ml / min every year.
Normal reference value of glomerular filtration rate
- (125 ± 15) ml / min for males; about 10% lower for females.