What is the toxicity of valproic acid?
The toxicity of valproic acid is an acute therapeutic reaction to the depression of the central nervous system and the disruption of metabolism. This drug is sold in a number of formats for the treatment of seizures and mania. The mechanism of action is somewhat unclear, but involves an increase in the concentration of neurotransmitter acid gamma-aminobutyic acid (GABA). Pacienti se mohou vyvinout reakcí tím, že berou příliš mnoho kyseliny valproové v jedné dávce nebo v důsledku chronické expozice vyššímu dávkám. This medicine may disrupt metabolism and can lead to liver and kidney problems. Stanovení účinné terapeutické dávky může trvat čas, která udržuje koncentrace v krvi účinné a zároveň snižuje rizika pro pacienta. Kdykoli by pacient mohl vyvinout komplikace jater a ledvin, zejména pokud dojde k anamnéze problémů neboPacient používá jiné léky, které mohou interagovat. Symptoms of damage to the central nervous system such as difficulty breathing, carefree speech and confusion. If the patient's blood is tested, it can detect an extremely highconcentration of drugs. Treatment of valproic acid toxicity may require in some cases to stabilize the patient's hospitalization.
people can overdose in many ways for this medicine. One involves taking too many tablets or damage to the prolonged release coatings to allow the drug to slowly distract into the patient's body. It is also possible to develop the toxicity of valpro chronic acid, where high doses over time slowly disrupt metabolism and can cause problems with the central nervous system. Other patients may be at risk of interaction with another drug that increases the effects of valproic acid.
If signs of central nervous system damage are developed in a patient on valpro acid, a medical provider may perform an assessment, including a blood test to see if the drug levels are dangerously high. It can determine that, which steps would be most effective for patient care. Once the patient is stable, the situation may be re -evaluated to determine whether the patient can safely use valpro acid safely or whether another remedy for checking seizures or mania should be considered. People with a history of valpro acid toxicity should make sure they are recorded on their graphs, so care providers are aware of the problem.