What is Klaustrum?
Claustrum is a relatively thin layer of gray matter located between the white tributaries of the outer capsule and the extreme basal ganglia capsule. Located middle to island bark and side to putamens. This structure is best observed through sagittal view, perspective observed when the body is divided into left and right sections. It can range from one to two millimeters thick and several centimeters long. Although its function is not yet fully determined, it is believed that it plays a role in emotions, excitement and conscious integration and can play a role in dementia states. It is said that its volume is only about 0.25% of the entire cortex. Its name is derived from the Latin word claustralis , which means isolated or separated. In fact, it is relatively isolated from the gray mass of the brain.
The interesting fact about this structure is that, unlike other parts of the brain, its cellular population is relatively homogeneous. In other parts of the brain, cells differentiate to different types of cells andThey perform different functions. There are only three main cell types in Klaustrum. Type 1 cells are large, have dendritic processes covered with spine and receive input from and give output to different areas of the brain. Cells of type 2 and 3, called interneurons, are limited to claustrum, lack spine and differ in terms of cell body size.
relatively little is known about the real function of this structure. Claustrum can play an important role in the integration of modality. When one perceives an object, it has different properties, including shape, color, weight, sound, speed and smell. These methods must be integrated to avoid confusion, and the claustrum of the PLV of this process seems to be a key role. It is also believed that this structure plays a role in functional timing, which means that it helps with the current processing of information.
It was found that people with dementia have abnormalities in their claustic. For example, when brain samples are examined in humans who have been diagnosed with Lewy's dementia or parkinsOn the disease, Klaustrum often has the inclusion of neurons alpha-Synuclein. These inclusions can be classified as beta amyloid, Lewy's body and Lewa Neurita. The presence of these inclusions is strongly associated with the dementia process.