What is the coagulation function?
Coagulation is a biological process by which blood hardens into a solid form. There are two related and critical functions of coagulation. First, it seals any violation of the primary organ protection of the human body from harmful external substances such as bacteria - skin. Secondly, it maintains the integrity of the closed circuit necessary for the body to supply oxygen and nutrients into all its tissues through the circulatory system. The process is also common for many inhumane animals and can be considered a natural version of the bandage. The walls of the containers are damaged, for example, when it pierces the skin or from the blunt force of the object, the blood flow is threatened by bleeding, more often called bleeding. The damaged location must be immediately connected to give the blood vessel a chance to start haemostasis, return to Astav normal flow without losing blood.
from start to finish is a complex process including both unique blood cells and chemicalé proteins, but it is fundamentally a linear cascade of triggering events. When endothelial tissue or inner wall of the blood vessel senses trauma, it is downloaded to reduce blood flow and minimize the damaged location. Tissue also releases a protein called thrombokinase to signal its anxiety. This triggers the reaction in two blood components: cell fragments called plates and protein called fibrinogen.
The amount of platelet is attracted and aggregates at the source point of the thrombokinase. The reaction of fibrinogen to thrombokinase has restructuring to another protein called fibrin, which holds the plates. In a very short time, it will be enough fibrin to wrap the cluster of plates to create a solid barrier called a clot. While there are many other well -known intermediate chemicals and steps in the process, this is the summary of the main function of coagulation - to create a clot, for connecting a damaged blood vessel.
If coagulation is successful, the blood vessel will relax and its endothelial tissue begins with a regenerative repair. Whenwill completely recover, the chemical enzyme called Plasmin in the blood breaks the clot apart by the dissolution of fibrin, which held it together. If the damage is due to the injury of the skin, the skin will also heal and the extruded part of the blood clot will be thrown away. Coagulation disorders include the inability to knock, such as rare haemophilia of bleeding disorders that leave the victims a high risk of demonstrating potentially fatal infections. A more common disorder is thrombosis when the blood clot is released and moves through the circulatory system, potentially to connect and disrupt blood flow to critical organs such as heart or brain.