What are the different methods for collecting stem cells?
There are three methods for collecting stem cells, including the collection of stem cells from bone marrow, blood and embryos. The stem cell harvest method of peripheral blood cells is preferred because it is considered safer and does not require any anesthesia for donors or patients. The collection of embryonic stem cells, which destroys the embryo to extract stem cells, is upset in moral and ethical reasons. The collection of bone marrow stem cells is an older method that is still used when insufficient stem cells are available with blood.
Peripheral blood collection can be autologous, which means from an external donor from a patient or alogenic. There are two intravenous devices in each arm, one drawing blood from the body and returning it. The machine separates stem cells from the blood before returning to the donor.
Before starting this method of collecting stem cells, the donor receives a medicine that promotes the formation of white cells in the bone marrow. Normally there are very little STEM cells available for SClimate in the blood. These drugs force bone marrow to produce a huge amount of white blood cells. The bone marrow cannot hold all these cells, so they are released into the blood where they can be harvested. Stem cell transplantation requires millions of these cells to function efficiently.
timing is important in this type of harvest to capture cells when they ripen into white blood cells. The drugs used in the procedure cause cells to quickly mature into other forms of unsuitable for harvest. Donors are usually tested often to measure the best time for harvesting.
Human embryo grows until hundreds of stem cells are formed. When these stem cells are harvested, the embryo dies. Research using animals has discovered ways to remove one cell from an embryo with eight cells that were manipulated by contact with other embryonic stem cells and cultivated its own stem cells. RemainingBryo with seven cells was implanted in the womb of the rat and produced normal offspring. Scientists hope to address the controversy in this area of stem cell extraction by maintaining the original embryo.
When stem cell harvest is allogeneous, the patient usually receives chemotherapy to treat cancer. These chemicals force its bone marrow to respond by producing white blood cells in the fight against foreign substances. The drugs have been developed to cause the same reaction in healthy donors who do not receive chemotherapy, and these drugs are usually given to cancer patients to increase stem cell production in their bone marrow.
bone marrow collection requires anesthesia before cell extraction. Large bones usually provide the best source of stem cells, with a pelvic bone preferred space for some doctors. This method of collecting stem cells is a more complex operation and usually leads to greater pain. It is used when sufficient stem cells to extract blood.
the collection of stem cells pErifer blood can be repeated until enough cells are available. The patient may take bone pain because the marrow works on the production of more blood and white blood cells. Usually, free -the -counter painkillers check the discomfort of the procedure. Recovery is commonly fast, without permanent side effects.